Results 71 to 80 of about 2,095,520 (306)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Models and Practice of Retail Location on the Romanian Market [PDF]

Amfiteatru Economic, 2017
This paper makes a review of the main types of location, respectively of probability models, gravity models, utility models, location- allocation, but also of new spatial analysis instruments.
Gerard Cazabat, , Mihaela Gabriela Belu, Ioan Popa , Dorel Mihai Paraschiv   +3 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Optimal Locations and Inner Products

Journal of Mathematical Analysis and Applications, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Dynamic calculation of an optimum arrangement of rotary wind turbines on floors of a compact multystoried wind farm

Вестник КазНУ. Серия математика, механика, информатика, 2018
In view of the deterioration of the ecological situation on the planet Earth and decreasing feedstock for conventional sources of energy it has recently become urgent creation of non-traditional, non-polluting and renewable energy sources.
Т. Кунакбаев, Д. Нигметов, В. Туреханова   +2 more
doaj  

Morphologie du réseau de communication et localisations optimales d'activités. Quelle mesure pour exprimer la forme d'un réseau ?

Cybergeo, 1997
L'objectif du présent article est de poser succinctement les problèmes que soulèvent la caractérisation de la forme d'un réseau par un - ou plusieurs - paramètre(s).
Hubert Beguin, Isabelle Thomas
doaj   +1 more source

Joint Optimization Framework for Operational Cost Minimization in Green Coverage-Constrained Wireless Networks

, 2017
In this work, we investigate the joint optimization of base station (BS) location, its density, and transmit power allocation to minimize the overall network operational cost required to meet an underlying coverage constraint at each user equipment (UE),
Hossain, Ashraf, Mishra, Deepak, Prasad, Ganesh   +2 more
core   +1 more source