Results 71 to 80 of about 5,095,233 (306)

A power flow mode theory based on a system's damping distribution and power flow design approaches [PDF]

, 2005
A power flow mode theory is developed to describe the natural power flow behaviour of a dynamic system based on its inherent damping distribution.
Xing, J.T., Xiong, Ye-Ping, Ye-Ping Xiong, J.T. Xing, Price, W.G., W.G. Price   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

QMODE+ ablation mode: optimal parameter setting and impedance-adapted strategies

Frontiers in Cardiovascular Medicine
BackgroundA new catheter (the QDOT-MICRO catheter) is used for high-power short duration (vHPSD) ablation.ObjectivesThis study aimed to optimize lesion formation in QMODE+ ablation (using QDOT-MICRO catheter) by clarifying effects of key parameters and ...
Xuesong Shi, Xuesong Shi, Mingyu Sun, Zulu Wang, Ming Liang, Zhiqing Jin, Jian Ding   +6 more
doaj   +1 more source

Optimal Sliding Mode Chaos Control of Direct-Drive Wave Power Converter

IEEE Access, 2019
In this paper, in order to investigate the chaos control problem of direct-drive wave power conversion system, the hydrodynamic model of Archimedes wave swing and the state equation of permanent magnet linear synchronous motor are analyzed, and a ...
Junhao Huang, Junhua Yang, Dongshen Xie, Danqi Wu   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Optimal Intrinsic Mode Function Based Detection of Motor Bearing Damages

Applied Sciences, 2019
This paper proposes a model which uses the greedy algorithm to select the optimal intrinsic mode functions (IMFs) of the empirical mode decomposition (EMD), namely the greedy empirical mode decomposition (GEMD) model.
Chun-Yao Lee, Kuan-Yu Huang, Yu-Hua Hsieh, Po-Hung Chen   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Optimal sliding mode controllers for attitude tracking of spacecraft [PDF]

, 2009
This paper studies two optimal sliding mode control laws using integral sliding mode control (ISM) for some spacecraft attitude tracking problems. Integral sliding mode control combining the first order sliding mode and optimal control is applied to ...
Zinober, A.S.I., C. Pukdeboon, A. S. I. Zinober, Pukdeboon, C.   +3 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source