Results 81 to 90 of about 774,682 (254)

How Many Topics? Stability Analysis for Topic Models

open access: yes, 2014
Topic modeling refers to the task of discovering the underlying thematic structure in a text corpus, where the output is commonly presented as a report of the top terms appearing in each topic. Despite the diversity of topic modeling algorithms that have
C. Lin   +13 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

A quarter-century of synthetic data in healthcare: Unveiling trends with structural topic modeling

open access: yesDigital Health
Objective To systematically map the research landscape of synthetic data in healthcare between 2000 and 2024, revealing prevalent topics and tracking their evolution over time and across geographic locations. Methods We applied structural topic modeling (
Billy Ogwel   +6 more
doaj   +1 more source

The Impact of Academic Publications over the Last Decade on Historical Bitcoin Prices Using Generative Models

open access: yesJournal of Theoretical and Applied Electronic Commerce Research
Since 2012, researchers have explored various factors influencing Bitcoin prices. Up until the end of July 2023, more than 9100 research papers on cryptocurrencies were published and indexed in the Web of Science Clarivate platform. The objective of this
Adela Bâra, Simona-Vasilica Oprea
doaj   +1 more source

Adaptive Task Assignment in Online Learning Environments

open access: yes, 2016
With the increasing popularity of online learning, intelligent tutoring systems are regaining increased attention. In this paper, we introduce adaptive algorithms for personalized assignment of learning tasks to student so that to improve his performance
Andersen, Per-Arne   +3 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Market Research Concerning Functional and Material Solutions Employed in Nursery Facilities

open access: yesArchives of Civil Engineering, 2019
A great number of non-functional child care facilities for children up to the age of three have been created in Poland to this day. This state of affairs may be the consequence of the low level of knowledge in this field, as well as few available studies
Radziszewska-Zielina E.   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Assessment of the sentiments expressed by traumatic brain injury patients and caregivers: A qualitative study based on in-depth interviews

open access: yesHeliyon
Introduction: Traumatic Brain Injury (TBI) is a significant public health concern that causes death, disability, and economic burden. Its repercussions affect physical, cognitive, emotional, and behavioral aspects of long-term care needs.
Raquel Mena-Marcos   +5 more
doaj   +1 more source

TREC video retrieval evaluation: a case study and status report [PDF]

open access: yes, 2004
The TREC Video Retrieval Evaluation is a multiyear, international effort, funded by the US Advanced Research and Development Agency (ARDA) and the National Institute of Standards and Technology (NIST) to promote progress in content-based retrieval from ...
Kraaij, Wessel   +2 more
core  

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