Results 81 to 90 of about 8,013,995 (308)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Assessment and enhancement of transfer capability for large-scale renewable generation base transmitted by voltage source converter based high voltage direct current system

International Journal of Electrical Power & Energy Systems
Voltage source converter based high voltage direct current transmission is a key method for transmitting large-scale renewable energy generation. The transfer capability of large-scale renewable generation base transmitted by voltage source converter ...
Shiyuan Chen, Shunjiang Lin, Yuerong Yang, Kaiyun Jiang, Mingbo Liu   +4 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Optimal Reactive Power Dispatch using Crow search Algorithm [PDF]

, 2018
The optimal reactive power dispatch is a kind of optimization problem that plays a very important role in the operation and control of the power system.
Lakshmi M, Ramesh Kumar A, A, Ramesh Kumar, M, Lakshmi   +3 more
core   +1 more source

Minimizing Real Power Losses Via Optimal Reactive Power Allocation and Distributed Generation Using Grey Wolf Optimizer

Journal of Engineering and Sustainable Development
An emphasis is placed on the optimal location and sizing of distributed generation and reactive power compensation to minimize real power loss in the Radial Distribution Network.
Bahaa Hussein Al IGEB, Petr P. Oschepkov , Mazin T Muhssin, Murtadha AL-KAABI, Ali abdulazeez, Saad K. Khalaf Khalaf   +5 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

A centralized reactive power compensation system for LV distribution networks

, 2014
A centralized reactive power compensation system is proposed for low voltage (LV) distribution networks. It can be connected with any bus which needs reactive power.
Foo, Yi Shyh Eddy, Hoay Beng Gooi, Shuai Xun Chen, Shao Feng Lu, Wang, M. Q., Yi Shyh Eddy Foo, Chen, Shuai Xun, Ming Qiang Wang, Gooi, Hoay Beng, Lu, S. F.   +9 more
core   +1 more source

Model-Free Optimal Volt-VAR Control of Wind Farm Based on Data-Driven Lift-Dimension Linear Power Flow

CSEE Journal of Power and Energy Systems
This paper proposes a reactive power and voltage optimal control method for wind farms based on data-driven power flow. Because no prior knowledge of wind farm parameters is necessary, the proposed method is model-free.
Li Guo, Zhaoning Liu, Zhongguan Wang, Xialin Li, Yixin Liu, Yuxuan Zhang, Xiaodi Zang, Chengshan Wang   +7 more
doaj   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source