Results 41 to 50 of about 482,042 (298)

Global testing under sparse alternatives: ANOVA, multiple comparisons and the higher criticism [PDF]

open access: yes, 2010
Testing for the significance of a subset of regression coefficients in a linear model, a staple of statistical analysis, goes back at least to the work of Fisher who introduced the analysis of variance (ANOVA).
Arias-Castro, Ery   +2 more
core   +4 more sources

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt   +76 more
wiley   +1 more source

Cautions on using the Before-After-Control-Impact design in environmental effects monitoring programs

open access: yesFACETS, 2017
Often the Before-After-Control-Impact (BACI) design is suggested as being a statistically powerful experimental design in environmental impact studies.
K.E. Smokorowski, R.G. Randall
doaj   +1 more source

On the Sample Information About Parameter and Prediction [PDF]

open access: yes, 2010
The Bayesian measure of sample information about the parameter, known as Lindley's measure, is widely used in various problems such as developing prior distributions, models for the likelihood functions and optimal designs.
Ehsan S. Soofi   +6 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Robust Superimposed Training Designs for MIMO Relaying Systems Under General Power Constraints

open access: yesIEEE Access, 2019
In this paper, we investigate the superimposed training matrix designs for the channel estimation of amplify-and-forward (AF) multiple-input multiple-output (MIMO) relaying systems under general power constraints.
Beini Rong   +3 more
doaj   +1 more source

Impulsive noise modeling and robust receiver design

open access: yesEURASIP Journal on Wireless Communications and Networking, 2021
Interference is an important limitation in many communication systems. It has been shown in many situations that the popular Gaussian approximation is not adequate and interference exhibits an impulsive behavior.
Laurent Clavier   +3 more
doaj   +1 more source

Selection and Screening Procedures to Determine Optimal Product Designs. (REVISED, April 1997) [PDF]

open access: yes, 1996
To compare several promising product designs, manufacturers must measure their performance under multiple environmental conditions. In many applications, a product design is considered to be seriously flawed if its performance is poor under any level of
Pan, Guohua, Santner, Thomas J.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Design Evaluation and Optimization of Population Pharmacokinetics Model Using an R Package PopED

open access: yesMathematics, 2023
The rising cost in drug development has led to continuous calls for more efficient and powerful design optimization and analysis tools for pkpd studies.
Howon Ryu, Weng Kee Wong
doaj   +1 more source

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