Results 71 to 80 of about 1,375,989 (278)

An optimal transport theory based approach for efficient dispatch of transactions in energy markets

open access: yesEnergy Conversion and Economics, 2023
Nowadays, transactive energy markets (TEMs) are emerging as interesting frameworks in deregulated power markets to control the balance of supply and demand in the entire electrical network.
Sreenivasulu Gumpu   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Weakly Noncollapsed RCD Spaces with Upper Curvature Bounds

open access: yesAnalysis and Geometry in Metric Spaces, 2019
We show that if a CD(K, n) space (X, d, f ℋn) with n ≥ 2 has curvature bounded above by κ in the sense of Alexandrov then f is constant.
Kapovitch Vitali, Ketterer Christian
doaj   +1 more source

Complex Quantum Networks: From Universal Breakdown to Optimal Transport

open access: yes, 2015
We study the transport efficiency of excitations on complex quantum networks with loops. For this we consider sequentially growing networks with different topologies of the sequential subgraphs.
Dolgushev, Maxim   +2 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Analytical and Geometric Foundations and Modern Applications of Kinetic Equations and Optimal Transport

open access: yesAxioms
We develop a unified analytical framework that systematically connects kinetic theory, optimal transport, and entropy dissipation through the novel integration of hypocoercivity methods with geometric structures.
Cécile Barbachoux, Joseph Kouneiher
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

A Numerical Method to solve Optimal Transport Problems with Coulomb Cost [PDF]

open access: yes, 2015
In this paper, we present a numerical method, based on iterative Bregman projections, to solve the optimal transport problem with Coulomb cost. This is related to the strong interaction limit of Density Functional Theory.
Benamou, Jean-David   +2 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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