Results 101 to 110 of about 90,500 (318)
Optimality Theory: Constraint Interaction in Generative Grammar
, 2002 This work develops a conception of grammar in which optimality with respect to a set of constraints defines well-formedness. The argument begins with a brief assessment of the promise of optimization-based approaches, focusing on issues of explanation ...
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Evaluating the complexity of optimality theory
, 2009 Idsardi (2006) claims that Optimality Theory (OT; Prince and Smolensky (1993/2004) is "in general computationally intractable" on the basis of a proof adapted from Eisner (1997). We take issue with this conclusion on two grounds.
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Adaptive intertemporal preferences in foraging-style environments
Frontiers in Neuroscience, 2013 Decision makers often face choices between smaller more immediate rewards and larger more delayed rewards. For example, when foraging for food, animals must choose between actions that have varying costs (e.g., effort, duration, energy expenditure) and ...
Michael T. Bixter, Christian C Luhmann
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Autosegmental spreading in optimality theory
, 2011 This paper is a shorter version of ROA-1009 'Harmony in harmonic serialism'. Some material is omitted, but the overall presentation is probably clearer.The publisher of the book in which this excerpt appears does not permit the archiving of this or any ...
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Derivational Phonology and Optimality Phonology: Formal Comparison and Synthesis
, 2003 This thesis conducts a formal comparison of Optimality Theoretic phonology with its predecessor, Rule-based Derivational phonology. This is done in three studies comparing (i) rule operations and Faithfulness constraint violations, (ii) serial rule ...
Norton, Russell James
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Selection for outbreeding in Varroa parasitising resistant honey bee (Apis mellifera) colonies
Ecology and Evolution, 2020 Parasitism is expected to select for counter‐adaptations in the host: driving a coevolutionary arms race. However, human interference between honey bees (Apis mellifera) and Varroa mites removes the effect of natural selection and restricts the evolution
Benjamin H. Conlon +5 more
doaj +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Non-computable functions in Optimality Theory
, 1999 Is Optimality Theory a constraining theory? A formal analysis shows that it is, if two auxiliary assumptions are made: (1) that only markedness and faithfulness constraints are allowed, and (2) that input and output representations are made from the same
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