Results 121 to 130 of about 90,500 (318)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Optimality Theory and the Minimalist Program
, 2006 In this paper I argue that an OT-approach to grammar is actually essential to minimalist investigations, because it dramatically widens the set of linguistic properties potentially reducible to interface conditions while at the same time dispensing with ...
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Optimality Theory and Minimalism: A Possible Convergence?
, 2006 This issue of Linguistics in Potsdam contains a number of papers that grew out of the workshop Descriptive and Empirical Adequacy in Linguistics held in Berlin on December 17-19 December, 2005.
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Features in Optimality Theory: A Computational Model
, 1999 This dissertation presents a computational model of Optimality Theory (OT) (Prince and Smolensky 1993). The model provides an efficient solution to the problem of candidate generation and evaluation, and is demonstrated for the realm of phonological ...
Heiberg, Andrea Jeanine +1 more
core +1 more source
Sparse model identification using orthogonal forward regression with basis pursuit and D-optimality [PDF]
, 2004 An efficient model identification algorithm for a large class of linear-in-the-parameters models is introduced that simultaneously optimises the model approximation ability, sparsity and robustness. The derived model parameters in each forward regression
Harris, C. J. +5 more
core +1 more source
GIS and AHP based modeling for landfill site selection (case study: west side of Mosul city)
Przegląd Naukowy Inżynieria i Kształtowanie Środowiska, 2019 The accumulation of large quantities of solid waste inside Mosul city becomes a real residential and municipal management problem. There are many reasons including the existence of unplanned dumping sites within the city boundaries, and the absence of ...
Raid M. Faisal, Mohammed F.A. Ahmed
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
First order optimality condition for constrained set-valued optimization [PDF]
A constrained optimization problem with set-valued data is considered. Different kind of solutions are defined for such a problem. We recall weak minimizer, efficient minimizer and proper minimizer.
Rocca Matteo +2 more
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The Learnability of Optimality Theory: An Algorithm and Some Basic Complexity Results
, 1995 If Optimality Theory (Prince & Smolensky 1991, 1993) is correct, Universal Grammar provides a set of universal constraints which are highly general, inherently conflicting, and consequently rampantly violated in the surface forms of languages. A language’
core +1 more source