Results 51 to 60 of about 238,335 (283)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
, 2012 We consider 1-qubit mixed quantum state estimation by adaptively updating measurements according to previously obtained outcomes and measurement settings.
C. R. Rao +12 more
core +1 more source
Quantum optimal control theory [PDF]
Journal of Physics B: Atomic, Molecular and Optical Physics, 2007 The control of quantum dynamics via specially tailored laser pulses is a long-standing goal in physics and chemistry. Partly, this dream has come true, as sophisticated pulse shaping experiments allow to coherently control product ratios of chemical reactions. The theoretical design of the laser pulse to transfer an initial state to a given final state
Werschnik, J., Gross, E. K. U.
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Optimality Theory as a Framework for Lexical Acquisition
, 2014 This paper re-investigates a lexical acquisition system initially developed for French.We show that, interestingly, the architecture of the system reproduces and implements the main components of Optimality Theory.
A. Arun +8 more
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Optimality theory and assessment of developing and disordered phonologies
Journal of Indian Speech Language & Hearing Association, 2015 Optimality theory (OT) is a comparatively recent linguistic theory which has been introduced in the early 1990s. OT's description of children's error patterns as patterns that are derived from a hierarchy of conflicting universal constraints has much ...
Froogh Shooshtaryzadeh
doaj +1 more source
Lipschitzian Regularity of the Minimizing Trajectories for Nonlinear Optimal Control Problems
, 2002 We consider the Lagrange problem of optimal control with unrestricted controls and address the question: under what conditions we can assure optimal controls are bounded?
Torres, Delfim F. M.
core +2 more sources