Results 41 to 50 of about 87,577 (219)

DESIGN AND IMPLEMENTATION OF NONLINEAR PID CONTROLLER FOR A QUADROTOR CONTROL

open access: yesJournal of Fundamental and Applied Sciences, 2018
The following article represents the control of an unmanned airborne vehicle (Quadcopter), using nonlinear PID controllers in order to control the altitude, as well as the attitudes (pitch, roll and yaw) of the Quadcopter.
O. Medjdoubi, A. Hazzab, A. Alalei
doaj   +1 more source

Design, commissioning and operation of a mini hybrid parabolic trough solar thermal power plant for direct steam generation

open access: yesSolar Energy Advances, 2023
Parabolic Trough Collectors (PTCs) are the most mature, reliable and widespread among Concentrated Solar Power (CSP) technologies for electricity generation.
Hamdi Kessentini   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Development of an ethical framework for the use of social robots in the care of individuals with major neurocognitive disorders: a qualitative study

open access: yesBMC Geriatrics
Background Despite the growing use of social robots in geriatric care, there is a lack of standardized ethical guidelines to inform and guide professionals in their implementation.
Caitlin Ware   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Molecular and Functional Study of Transient Receptor Potential Vanilloid 1-4 at the Rat and Human Blood–Brain Barrier Reveals Interspecies Differences

open access: yesFrontiers in Cell and Developmental Biology, 2020
Transient receptor potential vanilloid 1-4 (TRPV1-4) expression and functionality were investigated in brain microvessel endothelial cells (BMEC) forming the blood–brain barrier (BBB) from rat and human origins.
Huilong Luo   +12 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Diagnostics-linked Antimicrobial Surveillance: A Route to Patient-Centred Microbiology Diagnostics?

open access: yesInternational Journal of Infectious Diseases
Introduction: Microbiology diagnostics are widely recognised as an important tool in the fight against antimicrobial resistance (AMR), due to their ability to provide information to clinicians to inform antimicrobial treatment.
Dr Alex Howard   +5 more
doaj   +1 more source

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