Results 21 to 30 of about 94,494 (269)

Optimising homeostasis [PDF]

British Medical Bulletin, 2000
There is a wealth of experimental and clinical information showing that hypertension, hyperglycaemia, hyperthermia and intracranial hypertension are each independent indicators of a poor prognosis after stroke, but there is an astonishing lack of evidence from randomised controlled trials to tell us how to manage these problems, bearing in mind their ...
openaire   +2 more sources

Barriers and facilitators to the uptake of new medicines into clinical practice: a systematic review

BMC Health Services Research, 2021
Background Implementation and uptake of novel and cost-effective medicines can improve patient health outcomes and healthcare efficiency. However, the uptake of new medicines into practice faces a wide range of obstacles.
Kristina Medlinskiene, Justine Tomlinson, Iuri Marques, Sue Richardson, Katherine Stirling, Duncan Petty   +5 more
doaj   +1 more source

Empiric Unsupervised Drifts Correction Method of Electrochemical Sensors for in Field Nitrogen Dioxide Monitoring

Sensors, 2021
This paper investigates the long term drift phenomenon affecting electrochemical sensors used in real environmental conditions to monitor the nitrogen dioxide concentration [NO2].
Rachid Laref, Etienne Losson, Alexandre Sava, Maryam Siadat   +3 more
doaj   +1 more source

Personalising intravenous to oral antibiotic switch decision making through fair interpretable machine learning

Nature Communications
Antimicrobial resistance (AMR) and healthcare associated infections pose a significant threat globally. One key prevention strategy is to follow antimicrobial stewardship practices, in particular, to maximise targeted oral therapy and reduce the use of ...
William J. Bolton, Richard Wilson, Mark Gilchrist, Pantelis Georgiou, Alison Holmes, Timothy M. Rawson   +5 more
doaj   +1 more source

General practitioner practice-based pharmacist input to medicines optimisation in the UK: pragmatic, multicenter, randomised, controlled trial

Journal of Pharmaceutical Policy and Practice, 2021
Background Changing demographics across the UK has led to general practitioners (GPs) managing increasing numbers of older patients with multi-morbidity and resultant polypharmacy. Through government led initiatives within the National Health Service, an
Nadia Farhanah Syafhan, Sayer Al Azzam, Steven D. Williams, Wendy Wilson, Jayne Brady, Peter Lawrence, Mark McCrudden, Mustafa Ahmed, Michael G. Scott, Glenda Fleming, Anita Hogg, Claire Scullin, Robert Horne, Harblas Ahir, James C. McElnay   +14 more
doaj   +1 more source

Multi-Robot Exploration of Unknown Space Using Combined Meta-Heuristic Salp Swarm Algorithm and Deterministic Coordinated Multi-Robot Exploration

Sensors, 2023
Multi-robot exploration means constructing a finite map using a group of robots in an obstacle chaotic space. Uncertainties are reduced by distributing search tasks to robots and computing the best action in real time.
Ali El Romeh, Seyedali Mirjalili
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Development of a novel quantitative lateral flow assay for vancomycin for therapeutic drug monitoring

Scientific Reports
Antibiotic optimisation through therapeutic drug monitoring (TDM) is a key strategy in tackling antimicrobial resistance. However, current quantification methods rely on laboratory-based equipment, delaying timely dose adjustments.
Alaa Riezk, Vasin Vasikasin, Richard C. Wilson, Timothy M. Rawson, Anthony E. G. Cass, Alison H. Holmes   +5 more
doaj   +1 more source

Three optimisations for sharing [PDF]

Theory and Practice of Logic Programming, 2003
To improve precision and efficiency, sharing analysis should track both freeness and linearity. The abstract unification algorithms for these combined domains are suboptimal, hence there is scope for improving precision. This paper proposes three optimisations for tracing sharing in combination with freeness and linearity. A novel connection between
Jacob M. Howe, Andy King
openaire   +3 more sources

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source