Results 21 to 30 of about 88,363 (267)

cholangioscopy in liver grafts: a novel technique to assess the biliary tree during organ preservation and machine perfusion: a experimental non-clinical study [PDF]

Clinical Endoscopy
Background/Aims Biliary complications are a leading cause of morbidity after liver transplantation, but can be reduced using real-time assessment of the biliary tree.
Mark Ly, Ngee-Soon Lau, Joanna Huang, Hayden Ly, Kasper Ewenson, Nicole Mestrovic, Paul Yousif, Ken Liu, Avik Majumdar, Geoffrey McCaughan, Michael Crawford, Carlo Pulitano   +11 more
doaj   +1 more source

Empiric Unsupervised Drifts Correction Method of Electrochemical Sensors for in Field Nitrogen Dioxide Monitoring

Sensors, 2021
This paper investigates the long term drift phenomenon affecting electrochemical sensors used in real environmental conditions to monitor the nitrogen dioxide concentration [NO2].
Rachid Laref, Etienne Losson, Alexandre Sava, Maryam Siadat   +3 more
doaj   +1 more source

Barriers and facilitators to the uptake of new medicines into clinical practice: a systematic review

BMC Health Services Research, 2021
Background Implementation and uptake of novel and cost-effective medicines can improve patient health outcomes and healthcare efficiency. However, the uptake of new medicines into practice faces a wide range of obstacles.
Kristina Medlinskiene, Justine Tomlinson, Iuri Marques, Sue Richardson, Katherine Stirling, Duncan Petty   +5 more
doaj   +1 more source

Multi-Robot Exploration of Unknown Space Using Combined Meta-Heuristic Salp Swarm Algorithm and Deterministic Coordinated Multi-Robot Exploration

Sensors, 2023
Multi-robot exploration means constructing a finite map using a group of robots in an obstacle chaotic space. Uncertainties are reduced by distributing search tasks to robots and computing the best action in real time.
Ali El Romeh, Seyedali Mirjalili
doaj   +1 more source

Personalising intravenous to oral antibiotic switch decision making through fair interpretable machine learning

Nature Communications
Antimicrobial resistance (AMR) and healthcare associated infections pose a significant threat globally. One key prevention strategy is to follow antimicrobial stewardship practices, in particular, to maximise targeted oral therapy and reduce the use of ...
William J. Bolton, Richard Wilson, Mark Gilchrist, Pantelis Georgiou, Alison Holmes, Timothy M. Rawson   +5 more
doaj   +1 more source

General practitioner practice-based pharmacist input to medicines optimisation in the UK: pragmatic, multicenter, randomised, controlled trial

Journal of Pharmaceutical Policy and Practice, 2021
Background Changing demographics across the UK has led to general practitioners (GPs) managing increasing numbers of older patients with multi-morbidity and resultant polypharmacy. Through government led initiatives within the National Health Service, an
Nadia Farhanah Syafhan, Sayer Al Azzam, Steven D. Williams, Wendy Wilson, Jayne Brady, Peter Lawrence, Mark McCrudden, Mustafa Ahmed, Michael G. Scott, Glenda Fleming, Anita Hogg, Claire Scullin, Robert Horne, Harblas Ahir, James C. McElnay   +14 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Development of a novel quantitative lateral flow assay for vancomycin for therapeutic drug monitoring

Scientific Reports
Antibiotic optimisation through therapeutic drug monitoring (TDM) is a key strategy in tackling antimicrobial resistance. However, current quantification methods rely on laboratory-based equipment, delaying timely dose adjustments.
Alaa Riezk, Vasin Vasikasin, Richard C. Wilson, Timothy M. Rawson, Anthony E. G. Cass, Alison H. Holmes   +5 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Towards individualised treatment of urinary tract infections

Communications Medicine
Monitoring host- and pathogen-specific biomarkers alongside drug levels at the site of infection offers promise for personalised antimicrobial therapy.
Ellen V. Stadler, Alison Holmes, Danny O’Hare, Timothy M. Rawson   +3 more
doaj   +1 more source