Results 61 to 70 of about 676,204 (267)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Digital Ecosystems: Ecosystem-Oriented Architectures

open access: yes, 2011
We view Digital Ecosystems to be the digital counterparts of biological ecosystems. Here, we are concerned with the creation of these Digital Ecosystems, exploiting the self-organising properties of biological ecosystems to evolve high-level software ...
Briscoe, Gerard   +2 more
core   +1 more source

Improving communication with individuals experiencing Behavioural and Psychological Symptoms of Dementia (BPSD): an evaluative study of a co-designed video-based training programme for health professionals

open access: yesBMC Geriatrics
Background Behavioural and psychological symptoms of dementia (BPSD) are common, distressing manifestations of major neurocognitive disorders. Ineffective health professional communication exacerbates these symptoms, while conventional training rarely ...
Hermine Lenoir   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Developments in linear and integer programming [PDF]

open access: yes, 2002
In this review we describe recent developments in linear and integer (linear) programming. For over 50 years Operational Research practitioners have made use of linear optimisation models to aid decision making and over this period the size of problems ...
Darby-Dowman, K, Wilson, J M
core   +1 more source

Continuous Patient Monitoring With a Patient Centric Agent: A Block Architecture

open access: yesIEEE Access, 2018
The Internet of Things (IoT) has facilitated services without human intervention for a wide range of applications, including continuous remote patient monitoring (RPM).
Md. Ashraf Uddin   +3 more
doaj   +1 more source

Progress towards Analytically Optimal Angles in Quantum Approximate Optimisation

open access: yesMathematics, 2022
The quantum approximate optimisation algorithm is a p layer, time variable split operator method executed on a quantum processor and driven to convergence by classical outer-loop optimisation.
Daniil Rabinovich   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Conic geometric optimisation on the manifold of positive definite matrices

open access: yes, 2014
We develop \emph{geometric optimisation} on the manifold of Hermitian positive definite (HPD) matrices. In particular, we consider optimising two types of cost functions: (i) geodesically convex (g-convex); and (ii) log-nonexpansive (LN).
Hosseini, Reshad, Sra, Suvrit
core   +1 more source

Application of a new multi-agent Hybrid Co-evolution based Particle Swarm Optimisation methodology in ship design [PDF]

open access: yes, 2010
In this paper, a multiple objective 'Hybrid Co-evolution based Particle Swarm Optimisation' methodology (HCPSO) is proposed. This methodology is able to handle multiple objective optimisation problems in the area of ship design, where the simultaneous ...
Cui, Hao, Turan, O.
core   +1 more source

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