Results 71 to 80 of about 5,558,612 (273)
Object scale selection of hierarchical image segmentation with deep seeds
IET Image Processing, 2021 Hierarchical image segmentation is a prevalent technique in the literature for improving segmentation quality, where the segmentation result needs to be searched at different scales of the hierarchy to identify objects represented from various scales. In
Zaid Al‐Huda +3 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Interval optimization‐based scheduling of interlinked power, gas, heat, and hydrogen systems
IET Renewable Power Generation, 2021 The combined heat and power (CHP) plant is one of the emerging technologies of gas‐fired units, which plays an important role in reducing environmental pollutants and delivering high energy efficiency.
Nima Nasiri +6 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Simulation-based fitness landscape analysis and optimisation of complex problems
Technological and Economic Development of Economy, 2015 Widespread hard optimisation problems in economics and logistics are characterised by large dimensions, uncertainty and nonlinearity and require more powerful methods of stochastic optimisation that traditional ones. Simulation optimisation is a powerful
Galina Merkuryeva, Vitaly Bolshakov
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Tactics for improving computational performance of criticality analysis in state estimation
IET Generation, Transmission & Distribution, 2021 Power system state estimation is a needful tool for providing reliable data on the system operating conditions. As such, state estimation requires adequate data redundancy levels, which can be expressed in terms of the degrees of criticalities associated
Vinícius B. Braga Flôr +3 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Convex model predictive control for collision avoidance
IET Control Theory & Applications, 2021 This manuscript proposes a model predictive control for collision avoidance for the regulation problem of deterministic linear systems, which provides a priori guarantees of strong system theoretic properties, such as positive invariance and asymptotic ...
Saša V. Raković +4 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Ain Shams Engineering Journal, 2020 The growth of demand, the need for economic efficiency and optimal utilisation of electric power networks and the high cost of construction of new power networks result in inevitable challenges, such as overloading and excessive power transfer along ...
Ahmad AL Ahmad, Reza Sirjani
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