Results 91 to 100 of about 5,558,612 (273)
Optimisation of the High Efficiency Deep Grinding Process with Fuzzy Fitness Function and Constraints. [PDF]
This paper describes the application of two multi-objective optimisation techniques to the high efficiency deep grinding process. The process is modelled using a fuzzy expert system.
Tiwari, Ashutosh +7 more
core +1 more source
Applying network flow optimisation techniques to minimise cost associated with flood disaster. [PDF]
Okonta SD, Olaomi J.
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Branch Optimisation Techniques for Hardware Compilation
This paper explores using information about program branch probabilities to optimise reconfigurable designs. The basic premise is to promote utilization by dedicating more resources to branches which execute more frequently. A hardware compilation system has been developed for producing designs which are optimised for different branch probabilities. We
Henry Styles, Wayne Luk
openaire +3 more sources
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Formula constant optimisation techniques including variation of keratometer or corneal refractive index and consideration for classical and modern IOL formulae. [PDF]
Langenbucher A +4 more
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Post-stenting optimisation techniques in bifurcation percutaneous coronary interventions: much remains to be explored. [PDF]
Chieffo A, Beneduce A.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source

