Results 71 to 80 of about 10,104,704 (372)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Raccoon Optimization Algorithm

IEEE Access, 2019
Population-based meta-heuristic is a high-level method intended to provide sufficient solution for problems with incomplete information among a massive volume of solutions. However, it does not guarantee to attain global optimum in a reasonable time.
Sina Zangbari Koohi, Nor Asilah Wati Abdul Hamid, Mohamed Othman, Gafurjan Ibragimov   +3 more
doaj   +1 more source

Enhanced Flexible Algorithm for the Optimization of Slot Filling Factors in Electrical Machines

Energies, 2020
The continuous development in the field of industrial automation and electric mobility has led to the need for more efficient electrical machines with a high power density.
Armin Dietz, Antonino Oscar Di Tommaso, Fabrizio Marignetti, Rosario Miceli, Claudio Nevoloso   +4 more
doaj   +1 more source

Single candidate optimizer: a novel optimization algorithm

Evolutionary Intelligence, 2022
Single-solution-based optimization algorithms have gained little to no attention by the research community, unlike population-based approaches. This paper proposes a novel optimization algorithm, called Single Candidate Optimizer (SCO), that relies only ...
Tareq M. Shami, D. Grace, Alister G. Burr, P. Mitchell   +3 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Optimization Algorithms

Development of initial optimization and transmission matrix calculation algorithms. New concepts to account for refractive index variations with adaptive meshing, Levy statistics and Monte Carlo modelling of light propagation in complex ...
Benoit Liquet, Sarat Moka, Yoni Nazarathy   +2 more
  +6 more sources

Algorithm Engineering in Robust Optimization

, 2015
Robust optimization is a young and emerging field of research having received a considerable increase of interest over the last decade. In this paper, we argue that the the algorithm engineering methodology fits very well to the field of robust ...
A Agra, A Atamtürk, A Beck, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Erera, A Kasperski, A Kasperski, A Kasperski, A Kasperski, A Mutapcic, A Ouorou, A Sbihi, A Schöbel, A Soyster, A Takeda, AB Chassein, B Roy, C Bohle, C Büsing, C Büsing, C Liebchen, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Catanzaro, D Delling, D Golovin, DJ Alem, DJ Thuente, E Conde, E Conde, E Conde, E Conde, F Bruns, F Pérez-Galarce, F Taniguchi, G Calafiore, G Calafiore, GC Calafiore, H Aissi, H Aissi, H Iida, H Mausser, H Yaman, HE Mausser, I Averbakh, I Averbakh, J Goh, J Lin, J Löfberg, J Pereira, J Xu, JE Falk, JLG Velarde, JM Mulvey, JR Farias de, KS Goetzmann, L Jenkins, LE Ghaoui, M Bürger, M Fischetti, M Fischetti, M Fischetti, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Inuiguchi, M López, M Monaci, M Monaci, MC Campi, MK Zanjani, N Eggenberg, O Berman, P Adasme, P Kouvelis, P Sanders, P Zieliński, PC Bouman, R Kalai, R Khandekar, R Montemanni, R Montemanni, R Montemanni, R Reemtsen, S Cicerone, S Siddiqui, S Suzuki, TS Ng, U Feige, V Cacchiani, V Jeyakumar, X Song, Y Nikulin, Y Yin   +114 more
core   +1 more source

Anti-coronavirus optimization algorithm

Soft Computing, 2022
This paper introduces a new swarm intelligence strategy, anti-coronavirus optimization (ACVO) algorithm. This algorithm is a multi-agent strategy, in which each agent is a person that tries to stay healthy and slow down the spread of COVID-19 by observing the containment protocols.
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source