Results 31 to 40 of about 19,096,786 (283)

High-dimensional aerodynamic data modeling using a machine learning method based on a convolutional neural network

Advances in Aerodynamics, 2022
Modeling high-dimensional aerodynamic data presents a significant challenge in aero-loads prediction, aerodynamic shape optimization, flight control, and simulation.
Bo-Wen Zan, Zhong-Hua Han, Chen-Zhou Xu, Ming-Qi Liu, Wen-Zheng Wang   +4 more
doaj   +1 more source

Multi-objective topology design optimization combined with robust optimization

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2023
Topology optimization (TO), which is a design optimization technique that does not require design parameters, has been attracting attention. TO has a high degree of freedom and can obtain a novel design shape suitable for desired purposes.
Akito MARUO, Norihiko ITANI, Ayano HASOME, Takashi YAMAZAKI, Hajime IGARASHI   +4 more
doaj   +1 more source

Optimal Experimental Designs

The Annals of Mathematical Statistics, 1966
Abstract : This paper presents a number of results concerning the theory of the optimal design of experiments initiated and principal developed by Elfving, Kiefer and Wolfowitz. The paper contains approximately half expository and half new material. The proofs are mostly new and presented in a unified manner.
Karlin, Samuel, Studden, William J.
openaire   +2 more sources

Many-Objective Optimization Design of a Public Building for Energy, Daylighting and Cost Performance Improvement

Applied Sciences, 2020
The energy performance of buildings especially public buildings needs to be optimized together with environmental, social and cost performance, which can be achieved by the multiobjective optimization method.
Cheng Sun, Liu Qianqian, Yunsong Han
semanticscholar   +1 more source

Optimal experimental design for optimal process design: A trilevel optimization formulation

AIChE Journal, 2019
AbstractTypical optimal experimental design (OED) methods aim at minimizing the covariance matrix of the estimated parameters regardless of the intended application of the model that is being estimated. This can unnecessarily increase the experimental costs.
Walz, Olga, Djelassi, Hatim, Mitsos, Alexander   +2 more
openaire   +3 more sources

Learning-based ship design optimization approach [PDF]

, 2012
With the development of computer applications in ship design, optimization, as a powerful approach, has been widely used in the design and analysis process.
Cui, Hao, Sayer, Philip, Turan, Osman
core   +1 more source

‘Click Chemistry’ Synthesis of Novel Natural Product-Like Caged Xanthones Bearing a 1,2,3-Triazole Moiety with Improved Druglike Properties as Orally Active Antitumor Agents

Molecules, 2017
DDO-6101, a natural-product-like caged xanthone discovered previously in our laboratory based on the pharmacophoric scaffold of the Garcinia natural product gambogic acid (GA), shows potent cytotoxicity in vitro, but poor efficacy in vivo due to its poor
Xiang Li, Yue Wu, Yanyan Wang, Qidong You, Xiaojin Zhang   +4 more
doaj   +1 more source

A comprehensive review of cycloastragenol: Biological activity, mechanism of action and structural modifications

European Journal of Medicinal Chemistry Reports, 2022
Cycloastragenol (CAG) is a sapogenin of Astragaloside IV (AG-IV), isolated from the dried roots of legumes Astragalus mongolica or Astragalus membranaceus.
Mengting He, Ke Wang, Haojie Che, Huifang Wang, Kan Yang, Guiming Zhang, Jingchun Yao, Jinxin Wang   +7 more
doaj   +1 more source

Casting Design Optimization for Steam Turbine Emergency Stop Valve (ESV) Housing with Computational Casting Simulation Method [PDF]

, 2018
Design optimization casting emergency stop valve steam turbine, has been done with casting simulation using Magmasoft v5 software. By simulation, some casting design parameters are changed to get more optimal results.
F, B. N. (Budi), Harmadi, R. (Rudias), Herbandono, K. (Khamda), Krisnowo, A. (Agus)   +3 more
core   +1 more source

Flow structures and wall parameters on rotating riblet disks and their effects on drag reduction

Alexandria Engineering Journal, 2022
The demand of energy saving and loss mitigation in modern industry gives rise to drag reduction techniques such as micro groove/riblet ever since the last century.
Tong Liang, Yang Xu, Jiawen Li, Guobiao Cai   +3 more
doaj   +1 more source