Results 41 to 50 of about 55,356 (266)
Mesh Simplification With Appearance-Driven Optimizations
IEEE Access, 2020 In this work, we propose a novel solution for simplifying texture-mapped three-dimensional (3D) meshes. It simplifies a 3D triangular mesh to optimally preserve the visual appearance of the original texture-mapped model at reduced vertex budgets.
Yongzhang Xian +6 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
An Empirical Investigation of Early Stopping Optimizations in Proximal Policy Optimization
IEEE Access, 2021 Code-level optimizations, which are low-level optimization techniques used in the implementation of algorithms, have generally been considered as tangential and often do not appear in published pseudo-code of Reinforcement Learning (RL) algorithms ...
Rousslan Fernand Julien Dossa +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Measuring the Optimality of Hadoop Optimization
CoRR, 2013 In recent years, much research has focused on how to optimize Hadoop jobs. Their approaches are diverse, ranging from improving HDFS and Hadoop job scheduler to optimizing parameters in Hadoop configurations. Despite their success in improving the performance of Hadoop jobs, however, very little is known about the limit of their optimization ...
Woo-Cheol Kim +2 more
openaire +2 more sources
OPTIMIZING UPPER EXCAVATOR [PDF]
Fiabilitate şi Durabilitate, 2016 An essential element when establishing the balance of a bucket wheel excavator is the determination of the barycentre, the best results being thus obtained by weighting after having installed all the components.
Dragos Vasile VÎGA +2 more
doaj
An Overwiew of Evolution of Lexical Query Optimization Techniques
Труды Института системного программирования РАН, 2018 The presented overview is concerned with lexical query optimization and covers papers published in the last four decades. The paper consists of five sections.
N. A. Mendkovich, S. D. Kuznetsov
doaj +1 more source
Pinhão: An Auto-tunning System for Compiler Optimizations Guided by Hot Functions [PDF]
Journal of Universal Computer Science, 2019 The literature presents several auto-tunning systems for compiler optimizations, which employ a variety of techniques; however, most systems do not explore the premise that a large amount of program runtime is spent by hot functions which are the ...
Marcos Siraichi +2 more
doaj +3 more sources