Results 51 to 60 of about 55,356 (266)

Optimizations for Passive Electric Field Sensing

open access: yesSensors, 2022
Passive electric field sensing can be utilized in a wide variety of application areas, although it has certain limitations. In order to better understand what these limitations are and how countervailing measures to these limitations could be implemented,
Julian von Wilmsdorff, Arjan Kuijper
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

An Optimal Preparation for Studying Optimization [PDF]

open access: yesNeuron, 2000
Imagine a fly navigating through a forest at 2 m/s. In order to correct for the effects of the wind and other flight instabilities, the fly must continually estimate its heading direction if only to avoid running into a tree or inadvertently flying in circles. Given the striking prominence of eyes on a fly's body, it is not surprising that vision plays
openaire   +2 more sources

An efficient hybrid conjugate gradient method for unconstrained optimization and image restoration problems [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization
The conjugate gradient (CG) method is an optimization technique known for its rapid convergence; it has blossomed into significant developments and applications.
C. Souli   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Optimality in robot motion [PDF]

open access: yesCommunications of the ACM, 2014
Exploring the distinction between an optimal robot motion and a robot motion resulting from the application of optimization techniques.
Laumond, Jean-Paul   +2 more
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Optimization Controller Design of Full-Vehicle Suspension System Based on Bicubic Positive-Real Impedances Realizable with Five Passive Elements

open access: yesActuators
This article investigates the passive controller design problem for a full-vehicle suspension system, where the passive controller consists of four positive-real bicubic impedances realizable as two-terminal five-element damper–spring–inerter networks ...
Kai Wang, Yaodong Li, Jiamei Pu
doaj   +1 more source

Specifying and Executing Optimizations for Parallel Programs [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
Compiler optimizations, usually expressed as rewrites on program graphs, are a core part of all modern compilers. However, even production compilers have bugs, and these bugs are difficult to detect and resolve. The problem only becomes more complex when
William Mansky   +2 more
doaj   +1 more source

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