Results 101 to 110 of about 6,129,258 (331)

Growth Optimization of Thermophilic Bacteria Bacillus thermoamylovorans and Brevibacillus sp. in Producing Keratinolytic Enzyme [PDF]

open access: yes, 2015
Some thermophilic bacteria have been isolated from Tanjung Sakti hot spring. Two isolates which qualitatively showed keratinolytic activity, identified as Bacillus thermoamylovorans and Brevibacillus sp., were optimized the growth in producing ...
Muharni, M.   +2 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A procedure for the determination of proteolytic activity [PDF]

open access: yes, 1950
The difficulties introduced by the desire to maintain a constant pH during an enzyme-catalyzed hydrolysis of peptide-like substrates and at the same time to determine the extent of hydrolysis by an acid-base titration have been pointed out (1), but to ...
Iselin, Beat M., Niemann, Carl
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Mechanism-based site-directed mutagenesis to shift the optimum pH of the phenylalanine ammonia-lyase from Rhodotorula glutinis JN-1

open access: yesBiotechnology Reports, 2014
Phenylalanine ammonia-lyase (RgPAL) from Rhodotorula glutinis JN-1 stereoselectively catalyzes the conversion of the l-phenylalanine into trans-cinnamic acid and ammonia, and was used in chiral resolution of dl-phenylalanine to produce the d ...
Longbao Zhu   +4 more
doaj   +1 more source

Proses Klorinasi untuk Menurunkan Kandungan Sianida dan Nilai KOK pada Limbah Cair Tepung Tapioka [PDF]

open access: yes, 2010
Telah dilakukan pengolahan limbah cair tepung tapioka menggunakan proses klorinasi dengan Ca(OCl)2. Parameter yang dievaluasi adalah berat optimum Ca(OCl)2, pH optimum, dan waktu kontak optimum antara Ca(OCl)2 dengan limbah cair tepung tapioka dalam ...
Afrilianza, A. (Afrilianza)   +2 more
core  

A study on Effects of pH, Adsorbent Dosage, Time, Initial Concentration and Adsorption Isotherm Study for the Removal of Hexavalent Chromium (Cr (VI)) from Wastewater by Magnetite Nanoparticles

open access: yes, 2016
Magnetite nanoparticles synthesized in the laboratory were used for the removal of Hexavalent chromium (Cr (VI)) from synthetically prepared wastewater. The synthesized particles were characterized using scanning electron microscopy equipped with energy ...
K. Padmavathy, G. Madhu, P. Haseena
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Penentuan Ph dan Suhu Optimum untuk Aktivitas Ekstrak Kasar Enzim Lipase dari Kecambah Biji Karet (Hevea Brasiliensis) terhadap Hidrolisis Pko (Palm Kernel Oil) [PDF]

open access: yes, 2013
Determination of optimum pH and temperature for crude lipase enzyme activity from rubber seeds germination had been conducted. Rubber seed germination made by soaking time process, seed separation with shell\u27s and seed germination in temperature 27 ...
Nasution, R. A. (Rizki)
core  

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