Results 221 to 230 of about 704,312 (278)

Evidence of parental care as a newly identified reproductive isolating barrier

Journal of Animal Ecology, Volume 95, Issue 11, Page 2292-2305, November 2026.
Behavioural variation can contribute to reproductive isolation and can be an important driver of speciation. Here, we show that a previously undescribed mechanism, parental care, can function as a postzygotic reproductive isolating barrier when dysregulated in hybrids.
Colby Behrens, Meghan F. Maciejewski, Alexandra Sumarli, Gina Lucas, German Lagunas‐Robles, Kieran Samuk, Alison M. Bell   +6 more
wiley   +1 more source

Chronic optogenetic stimulation of dentate gyrus granule cells in mouse organotypic slice cultures synaptically drives mossy cell degeneration. [PDF]

Epilepsia
Koretz CC, Schneider R, Jungenitz T, Drakew A, Roeper J, Deller T.   +5 more
europepmc   +1 more source

GABAergic Network Dysregulation in Alcohol Use Disorder: Receptor–Transporter Interactions Driving the Transition From Goal‐Directed to Compulsive Behaviour

Addiction Biology, Volume 31, Issue 11, November 2026.
Astrocytic GAT3 regulates ambient GABA levels in the globus pallidus externus (GPe). Reduced GAT3 function enhances extrasynaptic GABAergic signalling and disrupts subthalamic nucleus (STN) regulation and cortical signal fidelity.ABSTRACTAlcohol use disorder (AUD) is characterized by a shift from controlled, goal‐directed drinking to compulsive ...
Hannah Aranda, Nathan Jones, Humza Haroon, Doo‐Sup Choi   +3 more
wiley   +1 more source

Differential NMDA‐Evoked Excitatory and Inhibitory Neuronal Responses Under In Vivo and Ex Vivo Conditions in 5xFAD Mice

European Journal of Neuroscience, Volume 64, Issue 9, November 2026.
ABSTRACT Alzheimer's disease (AD) is associated with profound disturbances in neuronal activity. While spontaneous neuronal hyperactivity is a well‐established feature of AD, how the disease affects stimulus‐evoked responses of excitatory and inhibitory neurons remains unclear.
Seowoo Lee, Taeyoung Park, Seung Won Chung, Minah Suh   +3 more
wiley   +1 more source

Optogenetic stimulation of the locus coeruleus enhances appetitive extinction in rats. [PDF]

Elife
Lui S, Brink AK, Corbit LH.
europepmc   +1 more source

Parkinson's disease under dopamine replacement therapy as a human framework for studying addiction‐relevant mechanisms

Psychiatry and Clinical Neurosciences, Volume 80, Issue 11, Page 877-888, November 2026.
Addiction is a chronic relapsing condition characterized by compulsive reward seeking and impaired behavioral control, associated with major individual and societal burden. Mechanistic investigation in humans remains constrained by ethical limitations, uncontrolled exposure histories, and ecological confounds.
Vanessa Fleury, Elvira Pirondini, Damien Benis, Tiffany Corbet, Gabriel Thorens, Christian Lüscher, Paul Krack   +6 more
wiley   +1 more source

Opto-Avoidance-Elevated Plus Maze protocol to study positive or negative valence upon optogenetic stimulation in the mouse brain. [PDF]

STAR Protoc
Serra GP, Georges F, Wallén-Mackenzie Å.   +2 more
europepmc   +1 more source

The what, which, when, why and who of Off responses in the auditory system

The Journal of Physiology, Volume 604, Issue 21, Page 8690-8701, 1 November 2026.
Abstract figure legend In this article, we will first review ‘What’ different mechanisms are involved in the generation of Off responses at the sub‐cortical and cortical level of the auditory system. Then, we evaluate ‘Which’ stimulus properties elicit Off responses at the different levels of the auditory system.
Jean‐Marc Edeline, Robert C. Liu
wiley   +1 more source

Bioorthogonal Chemistry in Neurobiology: From Imaging to Proteomics

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
This review highlights emerging strategies for labeling neuronal proteins, enabling visualization and quantitative analysis of their expression, localization, and dynamics. By combining genetic code expansion (GCE), metabolic labeling, and click chemistry‐based labeling, these approaches provide powerful routes to study proteins in specific cells and ...
Neil Taylor, João de Sousa‐Lourenço, Ivana Nikić‐Spiegel   +2 more
wiley   +1 more source

Optogenetic stimulation of the "Zusanli" acupoint alleviates inflammatory pain through active Wnt/β-Catenin and MAPK signaling pathway in rats. [PDF]

Heliyon
Chen R, Li M, Ding M.
europepmc   +1 more source