Results 171 to 180 of about 28,756 (283)

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

Smart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang, Huan Tang, Yue Pan, Mingle Li, Weijie Zhao, Kai Liu   +5 more
wiley   +1 more source

Optogenetics

, 2021
Maria G. Paez Segala, Loren L. Looger
openaire   +2 more sources

Genetic manipulation technologies for precise cellular control: a comparative review of five approaches. [PDF]

Front Bioeng Biotechnol
Xiao Q, Sun P, Liu J, Li J, Xu X, Cao Y, Wu Y, Ke C.   +7 more
europepmc   +1 more source

Optical Control of Therapeutic Synthetic Cells: Controlling Biomolecule Synthesis, Activation, and Communication

Small Methods, EarlyView.
Combining synthetic cells engineering, cell‐free expression, and optical regulation may enable a new generation of programmable synthetic cell platforms. By providing spatiotemporal control over biomolecule synthesis, activation, transport, release, and communication, light offers a versatile strategy for coordinating proteins, RNAs, peptides, and ...
Gia Bao Leon Hoang, Taniya Chakraborty
wiley   +1 more source

Optogenetic Strategies for Motor Recovery After Ischemic Stroke: Mechanisms and Therapeutic Implications. [PDF]

Cell Mol Neurobiol
Shen PX, Wang P, Wang HX.
europepmc   +1 more source

Evidence of parental care as a newly identified reproductive isolating barrier

Journal of Animal Ecology, EarlyView.
Behavioural variation can contribute to reproductive isolation and can be an important driver of speciation. Here, we show that a previously undescribed mechanism, parental care, can function as a postzygotic reproductive isolating barrier when dysregulated in hybrids.
Colby Behrens, Meghan F. Maciejewski, Alexandra Sumarli, Gina Lucas, German Lagunas‐Robles, Kieran Samuk, Alison M. Bell   +6 more
wiley   +1 more source

Proton pump rhodopsins for optogenetic manipulation of biological activities and beyond. [PDF]

J Biol Chem
Kojima K, Inokuchi M, Sudo Y.
europepmc   +1 more source

Post‐Trial Responsibilities for Participants Implanted With Neurosurgical Devices: A Qualitative Study

Bioethics, EarlyView.
ABSTRACT The issue of post‐trial responsibility is about what is owed to research participants after a clinical trial ends, who is responsible, and how long this responsibility must endure. Despite two decades of international guidance on this issue, research involving novel high‐risk interventions—such as implantable neurotechnologies—raises ...
Nathan Higgins, Adrian Carter, John Gardner   +2 more
wiley   +1 more source

Lights up on the embryonic dance: tools and applications of optogenetics in developmental biology. [PDF]

Genes Dev
Gao Y, Ho EK, Toettcher JE.
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source