Entrainment of prefrontal theta synchrony increases interbrain coupling and enhances social interaction in mouse models of autism. [PDF]
Hwang E +9 more
europepmc +1 more source
Looking for trouble: A common threat‐detection mechanism underlying pain, fear, and anxiety
I put forward a novel cognitive architecture for pain, fear, and anxiety, according to which these three capacities are underpinned by a common threat‐detection mechanism. This mechanism takes information about potential threats as input, assesses whether the threat is actual and, if it deems it is, outputs a threat representation.
Luca Barlassina
wiley +1 more source
Seizure-Inducible Risks of In Vivo Optogenetic Manipulations. [PDF]
Zhu X +10 more
europepmc +1 more source
Guard cell size and initial conductance influence stomatal closure kinetics
Conceptual overview of the two hypotheses linking stomatal anatomy to closure kinetics. Summary In fluctuating environments, the kinetics of stomatal opening and closing influence the balance between carbon gain and water loss. Smaller guard cells may respond faster to fluctuating environmental conditions because of their greater surface area for ...
Christopher D. Muir, Wei Shen Lim
wiley +1 more source
Activation of silent synapses driven by emerging technologies: mechanisms, disease associations, and prospects for clinical translation. [PDF]
Li Y +8 more
europepmc +1 more source
Addiction is a chronic relapsing condition characterized by compulsive reward seeking and impaired behavioral control, associated with major individual and societal burden. Mechanistic investigation in humans remains constrained by ethical limitations, uncontrolled exposure histories, and ecological confounds.
Vanessa Fleury +6 more
wiley +1 more source
Wiley is pleased to announce the recent acquisition of the prestigious Encyclopedia of Life Sciences (ELS) from the Nature Publishing Group.
"The most ambitious single source reference source ever produced in the biological sciences"
—American Reference Books Annual
Spanning the entire spectrum of life science ...
Peter Hegemann, Carol Dieckmann
wiley +1 more source
Prefrontal parvalbumin neurons mediate working memory in a task demand-dependent manner. [PDF]
Dexter TD +10 more
europepmc +1 more source
Far‐field bioluminescent immune cell–mediated photodynamic therapy is limited by photon flux
Bioluminescent immune cell‐mediated photodynamic therapy uses tumor‐homing, luciferase‐expressing immune cells as internal light sources to activate photosensitizers in deep‐seated and/or micrometastatic tumors. Using both experiments and computational simulations, we find that this approach delivers insufficient far‐field energy to tumor cells to ...
Ji Tae Park +8 more
wiley +1 more source
Engineering controllable CAR T-cell therapies: from binary safety switches to programmable immunity. [PDF]
Smirnov S +3 more
europepmc +1 more source

