Results 201 to 210 of about 28,756 (283)

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

The Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Optogenetics for Investigating and Targeting Hallmark Traits of Cancer. [PDF]

Biomolecules
Kienbacher H, Hashim M, Grusch M.
europepmc   +1 more source

Update on cellular expression and function of ANO1 channels in urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley   +1 more source

Layer 1 NDNF interneurons modulate thalamocortical input to the auditory cortex. [PDF]

iScience
Tao J, Chen Y, Polat M, Li SC, Chen X, Zhao Z.   +5 more
europepmc   +1 more source

The what, which, when, why and who of Off responses in the auditory system

The Journal of Physiology, EarlyView.
Abstract figure legend In this article, we will first review ‘What’ different mechanisms are involved in the generation of Off responses at the sub‐cortical and cortical level of the auditory system. Then, we evaluate ‘Which’ stimulus properties elicit Off responses at the different levels of the auditory system.
Jean‐Marc Edeline, Robert C. Liu
wiley   +1 more source

Transforming healthcare through in-body bioelectronic systems. [PDF]

Nat Commun
Ceto S, Elshove SA, Wu M, Ramadi K, Tondera C, Minev IR, Srinivasan S, Lee K, Gora MJ, Rogers J, Kathe C, Hutson TH.   +11 more
europepmc   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

All-optical closed-loop control of human cardiomyocyte networks exploiting holographic optogenetics. [PDF]

Commun Eng
Wendland R, Schmieder F, Sikandar MA, Knüppel FP, Zimmermann WH, Bergmann O, Büttner L, Czarske JW.   +7 more
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

An Implantable Optogenetics-Engineered Hydrogel for Amelioration of Rheumatoid Arthritis through Light-Controlled Metabolic Reprogramming of Synovial Macrophages. [PDF]

Adv Sci (Weinh)
Hu D, Sun Y, Lu Q, Zhang Y, Li J, Hou H, Wang H, Tang H, Zhang Y, Zheng X, Mei Q.   +10 more
europepmc   +1 more source