Results 181 to 190 of about 21,147 (255)

Retrograde optogenetics reveals sensorimotor convergence within a corticotectal pathway of non-human primates. [PDF]

Curr Biol
Yu X, Gopal A, Inoue KI, Bohlen MO, Kuczewski GM, Sommer MA, Nienborg H, Takada M, Hikosaka O.   +8 more
europepmc   +1 more source

Astrocytes in Genetic Epilepsies: Supporting Actor or Key Player?

Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.
Astrocytes contribute to the pathophysiology of acquired epilepsy. However, less is known about their contribution to genetic epilepsy syndromes which often exhibit frequent comorbidity with neurodevelopmental and psychiatric disorders. Epileptic seizures are also frequently present in neurodevelopmental disorders.
Jenny Lange, Erica Zhao, Ellie O'Connell, Olivia Gillham, Amy McTague   +4 more
wiley   +1 more source

Feature-tuned synaptic inputs to somatostatin interneurons drive context-dependent processing. [PDF]

Neuron
Hendricks WD, Sadahiro M, Mossing D, Veit J, Adesnik H.   +4 more
europepmc   +1 more source

Injectable Artificial Photoreceptors: STEM Cell Functional Integration and in vivo Electrophysiological Validation in Retinal Degeneration Models

Small Science, Volume 6, Issue 8, August 2026.
Artificial photoreceptors are engineered to efficiently absorb light, with the strongest sensitivity in the green region of the visible spectrum. Upon illumination, they generate electrical signals that activate retinal ganglion cells, which are typically unaffected by disease, enabling transmission of visual information to the brain.
Afshin Izadian, Ali Torkashvand, Benjamin Allan McCall, Yong Gao, Christine M. Taylor, Fateme Karimi Hafshejani, Arupratan Das, Michelle L. Surma, Sunland Gong, Amir Reza Hajrasouliha   +9 more
wiley   +1 more source

Zebrafish as a Model for Cardiovascular Disease Using Nanotechnology and Emerging Optogenetic Tools. [PDF]

Biomedicines
Nguyen P, Avila V, Lee J.
europepmc   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, Volume 7, Issue 4, August 2026.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Bridging the translational gap in systems neuroscience: from circuit mechanisms to clinical therapeutics. [PDF]

Front Pharmacol
Wang A, Ye J, Li J, Chen X, Wang Q, Wu K.   +5 more
europepmc   +1 more source

Cortical‐Hypothalamic Assembloids Uncover the Cortical Regulation of Hypothalamic Responses to Fatty Acid

Cell Proliferation, Volume 59, Issue 8, August 2026.
By assembling cortical‐hypothalamic circuits, we show that cortical input protects hypothalamic neurons from fatty acid‐induced damage, which activates PGC1α to boost mitochondrial function. This reveals a cortico‐hypothalamic axis that defends against metabolic stress.
Mengdan Tao, Xiaowen Du, Qi Chen, Wenxin Mu, Shuning Lou, Xu Zhang, Min Xu, Jiting Li, Yuxuan Guo, Wanying Zhu, Yan Liu   +10 more
wiley   +1 more source

Sonogenetics for precision medicine: from molecular toolkit to clinical translation. [PDF]

Theranostics
Yu X, Pu M, Wang R, Ran H.
europepmc   +1 more source

Phenotypic Behavioural Effects of Genetic Deletion of the Vesicular Glutamate Transporter 3 in 5‐Hydroxytryptamine Neurons

Genes, Brain and Behavior, Volume 25, Issue 4, August 2026.
VGLUT3 in 5‐HT neurons is involved in some aspects of learning, here in association with learning for reward, although not anxiety‐like behaviour. ABSTRACT A major subpopulation of 5‐hydroxytryptamine (5‐HT) neurons expresses the vesicular glutamate transporter 3 (VGLUT3) allowing the co‐release of glutamate.
L. Sophie Gullino, Nida Chabbah, Spatika Jayaram, Raquel Pinacho, Salah El Mestikawy, Stéphanie Daumas, David M. Bannerman, Trevor Sharp   +7 more
wiley   +1 more source