Results 41 to 50 of about 86,733 (198)

Who writes «the-book-that-I-do-not-write» ? Appellate capacity in Cixous' early and late works

Feminismo/s, 2006
Reading three recent texts of Cixous Les Rêveries de la femme sauvage, Tours promises et Le jour où je n’étais pas là, this article wants to explore the question of pairing or doubling (the mother, brother, sister, daughter, the Twin Towers, the ...
Cathérine Mavrikakis
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Los inicios de la experiencia coopeativa Mondragón

Revista de Estudios Cooperativos, 2014
Este artículo analiza los orígenes y la evolución inicial de la Experiencia Cooperativa Mondragón (ECM). A lo largo de estas tres décadas (1955-1985), se produce el surgimiento y la consolidación de la ECM. Esta Experiencia, radicalmente innovadora en su
Rafael Altuna, Eguzki Urteaga
doaj   +1 more source

Os sentidos da escritura em Orígenes

, 2022
O objetivo deste artigo é apresentar os três sentidos (literal, moral e espiritual) das Escrituras em Orígenes, esclarecendo alguns aspectos essenciais para se compreendê-las.
Marcus Reis Pinheiro, Rodiny Santos Berçot Junior   +1 more
core   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

Herida y nupcialidad en orígenes y Teresa de Ávila. El lenguaje poético-místico de la identidad de Jesús

Cuadernos de Teología - Universidad Católica del Norte, 2013
La poesía mística cristiana le debe a la interpretación origenista del Cantar de los Cantares la configuración de algunas de sus figuras más perdurables y Representativas como la herida de amor, los sentidos espirituales y la unión nupcial.
Cecilia Inés Avenatti De Palumbo
doaj   +1 more source

Sociología del Deporte en España: una actualización (2005-2017). [Sociology of Sport in Spain: an update (2005-2017)]. [PDF]

Revista Internacional de Ciencias del Deporte, 2018
El presente artículo comienza explicando cuáles son los orígenes de la Sociología del Deporte en España los cuales que se sitúan en los tiempos de la Transición (1975-1983); durante estos años, el deporte se va convirtiendo progresivamente de ser un ...
Nuria Puig, Anna Vilanova, Pau Mateu
doaj   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source