Results 31 to 40 of about 1,810,829 (308)

Sodium-glucose co-transporter 2 (SGLT2) inhibitors: a growing class of anti-diabetic agents

open access: yesDrugs in Context, 2014
Although several treatment options are available to reduce hyperglycemia, only about half of individuals with diagnosed diabetes mellitus (DM) achieve recommended glycemic targets.
Eva M Vivian
doaj   +1 more source

Nasal Drug Delivery Systems: An Overview [PDF]

open access: yes, 2015
Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades ...
Conway, Barbara R.   +3 more
core   +1 more source

Recent Progress in Diatom Biosilica: A Natural Nanoporous Silica Material as Sustained Release Carrier

open access: yesPharmaceutics, 2023
A drug delivery system (DDS) is a useful technology that efficiently delivers a target drug to a patient’s specific diseased tissue with minimal side effects.
Hayeon Lim   +7 more
doaj   +1 more source

Transport of therapeutics across intestinal epithelium [PDF]

open access: yes, 2016
This chapter focuses on the oral administration of therapeutics. Patients prefer oral administration because it is painless and simple to implement.
E. Roger, F. Lagarce, S. Muro
core   +4 more sources

An investigation of acute effects at various doses of malathion on glucose homeostasis and insulin resistance in rat liver, pancreas and serum [PDF]

open access: yes, 2020
Objective. This study investigates acute effects of various doses of Malathion on glucose homeostasis and insulin resistance in rat. Methods. Rats were randomly divided into four groups of 6 animals each. Corn oil was given orally to Group 1.
Ekremoğlu, Murat   +4 more
core   +3 more sources

Inhaled Insulin: Intrapulmonary or Intranasal? [PDF]

open access: yes, 2012
Initial attempts delivered the insulin hormone intramuscularly, intravenously, and eventually subcutaneously. Other routes of administration of the drug were explored.
Danish Ahmed   +3 more
core   +2 more sources

Anti-Inflammatory Activity of Chlorogenic Acid on Macrophages: A Simplified Simulation of Pharmacokinetics Following Ingestion Using a Windup Syringe Pump

open access: yesApplied Sciences, 2023
Cell-culture-based drug tests are usually performed in an instantaneous delivery manner. However, in vivo pharmacokinetic studies have shown a steady increase in the concentration of bioactive compounds in the plasma following oral administration, with ...
Lei Cao   +3 more
doaj   +1 more source

Orally administrated Lactobacillus gasseri TM13 and Lactobacillus crispatus LG55 can restore the vaginal health of patients recovering from bacterial vaginosis

open access: yesFrontiers in Immunology, 2023
Bacterial vaginosis (BV) is a common infection of the lower genital tract with a vaginal microbiome dysbiosis caused by decreasing of lactobacilli. Previous studies suggested that supplementation with live Lactobacillus may benefit the recovery of BV ...
Fengyuan Qi   +38 more
doaj   +1 more source

Genotoxic evaluation of polymeric nanoparticles

open access: yesFrontiers in Genetics, 2015
An important strategy for optimizing the therapeutic efficacy of many conventional drugs is the development of polymeric nanoparticles (NPs), as it may expand their activities, reduce their toxicity, increase their bioactivity and improve biodistribution.
Tamara Iglesias Alonso
doaj   +1 more source

Oral Probiotic Expressing Human Ethanol Dehydrogenase Attenuates Damage Caused by Acute Alcohol Consumption in Mice

open access: yesMicrobiology Spectrum, 2023
Alcohol is an essential drug in human life with multiple medical functions, but excessive alcohol intake, even a single episode of binge drinking, can cause serious damage.
Xiaoxiao Jiang   +9 more
doaj   +1 more source

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