Results 21 to 30 of about 601,354 (269)
Pentapartite fractionation of particles in oral fluids by differential centrifugation
Oral fluids (OFs) contain small extracellular vesicles (sEVs or exosomes) that carry disease-associated diagnostic molecules. However, cells generate extracellular vesicles (EVs) other than sEVs, so the EV population is quite heterogeneous.
Chiho Hiraga +9 more
doaj +1 more source
African swine fever virus (ASFV) causes a highly contagious and severe hemorrhagic viral disease with high mortality in domestic pigs of all ages. Although the virus is harmless to humans, the ongoing ASFV epidemic could have severe economic consequences
Jiwon Choi +12 more
doaj +1 more source
Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner
Hippo and Wnt pathways are important for cancer development, and they can cross talk; however, the mechanisms behind this connection are unknown. Here the authors show that DVL (a scaffold protein in the Wnt pathway) regulates the shuttling of YAP (a key
Yoonmi Lee +17 more
doaj +1 more source
PLAG1, SOX10, and Myb Expression in Benign and Malignant Salivary Gland Neoplasms [PDF]
Background Recent findings in molecular pathology suggest that genetic translocation and/or overexpression of oncoproteins is important in salivary gland tumorigenesis and diagnosis.
Ji Hyun Lee +8 more
doaj +1 more source
Case Report: Papillary Lesions at the Mouth Floor May Mimic Sialadenoma Papilliferum
Salivary gland tumor Sialadenoma papilliferum (SialP) clinically resembles papillary epithelial lesions, such as squamous papilloma (SqP) or verrucous leukoplakia.
Dawool Han +3 more
doaj +1 more source
Limocitrin induced cellular death through ERK pathways in human oral squamous cell cancer
This study sought to investigate the anticancer efficacy of limocitrin on two distinct human oral cancer cell lines. At first, we evaluated the effect of limocitrin on the proliferation of OSCC cells (SCC-9 and SCC-47) using MTT and colony formation ...
Bharath Kumar Velmurugan +6 more
doaj +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Assembly and activation of the Hippo signalome by FAT1 tumor suppressor
Dysregulation of the Hippo signaling is a frequent event in human malignancies, but the molecular mechanisms remain unclear. Here the authors show that in head and neck squamous carcinoma, FAT1 interacts with the Hippo signaling complex, resulting in the
Daniel Martin +20 more
doaj +1 more source
Case report: Ghost cell odontogenic carcinoma in a dog: diagnostics and surgical outcome
A 6 year-old spayed female Poodle presented with a mandibular mass. Radiographic examination revealed osteolysis from the right mandibular canine to the fourth premolar, along with horizontal bone loss and dorsal displacement of the right mandibular ...
Chun-Geun Kim +5 more
doaj +1 more source

