Results 91 to 100 of about 124,757 (203)

IgE-mediated cow's milk allergy in Brazilian children: Outcomes of oral food challenge. [PDF]

World Allergy Organ J, 2023
Aquilante BP, Castro APBM, Yonamine GH, de Barros Dorna M, Barp MF, Martins TPDR, Pastorino AC.   +6 more
europepmc   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Irradiation does not impact the immunogenicity of food flours used for oral immunotherapy

Journal of Allergy and Clinical Immunology: Global
Background: Peanut and tree nut flours are considered drug products by the US Food and Drug Administration when used during oral immunotherapy clinical trials and oral food challenges and must meet specific standards for microbial contamination and ...
Timothy P. Moran, MD, PhD, Anusha Penumarti, PhD, Robert M. Immormino, PhD, Talia Northup, BS, Rishu Guo, PhD, Janelle Kesselring, BS, Andrew Turner, BS, Priscilla Mathai, BS, Jessica R. Humphrey, MS, Johanna M. Smeekens, PhD, Edwin H. Kim, MD, MS, Yamini V. Virkud, MD, MA, MPH, Patricia C. Fulkerson, MD, PhD, Michael D. Kulis, PhD   +13 more
doaj   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Hospital oral food challenge tests in the coronavirus disease 2019 pandemic: A nationwide survey. [PDF]

Clin Transl Allergy, 2023
Yanagida N, Sugizaki C, Sato S, Ebisawa M.   +3 more
europepmc   +1 more source

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

Advanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang, Jiaxin Tian, Xiaolong Zhu, Xiao Li, Xiangshu Qiu, Yuanyuan Li, Ben Zhong Tang, Ning Shi   +7 more
wiley   +1 more source

Geographical discrepancy in oral food challenge utilization based on Canadian billing data. [PDF]

Allergy Asthma Clin Immunol, 2023
El Baba A, Jeimy S, Soller L, Kim H, Begin P, Chan ES.   +5 more
europepmc   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Evaluation of early laryngeal reaction at oral food challenge. [PDF]

J Allergy Clin Immunol Glob, 2022
Nakamura T, Okada Y, Maeda M, Kamiya T, Imai T.   +4 more
europepmc   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source