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Metabolic Contrasts Between Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: II. Observations Using the Oral Glucose Tolerance Test

open access: yesDiabetes Care, 2018
OBJECTIVE To compare oral glucose tolerance test (OGTT) glucose, C-peptide, and insulin responses and insulin sensitivity in youth and adults with impaired glucose tolerance (IGT) or recently diagnosed type 2 diabetes. RESEARCH DESIGN AND METHODS A total

semanticscholar   +1 more source

High prevalence of undiagnosed impaired glucose tolerance in patients with rheumatoid arthritis

open access: yesSAGE Open Medicine, 2022
Objectives: Although the risk of diabetes mellitus has been recognised in rheumatoid arthritis, undiagnosed dysglycaemia remained under-reported. The study aimed to determine the prevalence and associated factors of dysglycaemia among patients with ...
Nur ‘Aini Eddy Warman   +6 more
doaj   +1 more source

Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND: The prevalence of overweight is increasing globally and has become a serious health problem. Low-grade chronic inflammation in overweight subjects is thought to play an important role in disease development.
Suzan Wopereis   +9 more
doaj   +1 more source

Predicting long-term type 2 diabetes with support vector machine using oral glucose tolerance test

open access: yesbioRxiv, 2019
Diabetes is a large healthcare burden worldwide. There is substantial evidence that lifestyle modifications and drug intervention can prevent diabetes, therefore, an early identification of high risk individuals is important to design targeted prevention
H. Abbas   +6 more
semanticscholar   +1 more source

The Uptake of Screening for Type 2 Diabetes and Prediabetes by Means of Glycated Hemoglobin versus the Oral Glucose Tolerance Test among 18 to 60-Year-Old People of South Asian Origin: A Comparative Study.

open access: yesPLoS ONE, 2015
BackgroundDirect comparisons of the effect of a glycated haemoglobin measurement or an oral glucose tolerance test on the uptake and yield of screening in people of South Asian origin have not been made. We evaluated this in 18 to 60-year-old South Asian
Irene G M van Valkengoed   +4 more
doaj   +1 more source

Insulin resistance and systemic metabolic changes in oral glucose tolerance test in 5340 individuals: an interventional study

open access: yesBMC Medicine, 2019
BackgroundInsulin resistance (IR) is predictive for type 2 diabetes and associated with various metabolic abnormalities in fasting conditions. However, limited data are available on how IR affects metabolic responses in a non-fasting setting, yet this is
Qin Wang   +8 more
semanticscholar   +1 more source

Plasma metabolic signatures of healthy overweight subjects challenged with an oral glucose tolerance test [PDF]

open access: yes, 2022
Insulin secretion following ingestion of a carbohydrate load affects a multitude of metabolic pathways that simultaneously change direction and quantity of interorgan fluxes of sugars, lipids and amino acids. In the present study, we aimed at identifying
Rundle, M   +59 more
core   +1 more source

Time to Glucose Peak During an Oral Glucose Tolerance Test Identifies Prediabetes Risk

open access: yesClinical Endocrinology, 2017
Morphological characteristics of the glucose curve during an oral glucose tolerance test (OGTT) (time to peak and shape) may reflect different phenotypes of insulin secretion and action, but their ability to predict diabetes risk is uncertain.
S. Chung   +11 more
semanticscholar   +1 more source

Normal Glucose Tolerance with a High 1-Hour Postload Plasma Glucose Level Exhibits Decreased β-Cell Function Similar to Impaired Glucose Tolerance [PDF]

open access: yesDiabetes & Metabolism Journal, 2015
BackgroundSubjects with normal glucose tolerance (NGT) who have a high 1-hour postload plasma glucose level (≥155 mg/dL; NGT 1 hour-high) have been shown to be at higher risk for type 2 diabetes than subjects with NGT 1 hour-low postload plasma glucose ...
Tae Jung Oh   +7 more
doaj   +1 more source

Delay in glucose peak time during the oral glucose tolerance test as an indicator of insulin resistance and insulin secretion in type 2 diabetes patients

open access: yesJournal of Diabetes Investigation, 2018
Previous studies have shown that glucose peak time during the oral glucose tolerance test varies in type 2 diabetes patients; however, characteristics of this heterogeneity remain unclear. This research aimed to investigate the characteristics of delayed
Xin-Lei Wang   +10 more
semanticscholar   +1 more source

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