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Oral immunotherapy in pediatrics
Pediatric Allergy and Immunology, 2020AbstractIgE‐mediated food allergy (FA) has been emerging as a public health priority, mainly in children. It represents a heavy burden for the entire society and not only for the patients and their families. There is evidence that in children with persistent FA, at least to cow's milk, hen's egg, and peanut, oral immunotherapy (OIT) may increase the ...
Arasi S., Castagnoli R., Pajno G. B.
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Sublingual and oral immunotherapy
Immunology and Allergy Clinics of North America, 2004Sublingual immunotherapy (SLIT) is a viable alternative to the subcutaneous route for the treatment of respiratory allergy, whereas the pure oral route has been abandoned because of its lack of efficacy. The main distinctive feature of SLIT is its optimal safety profile, which has been demonstrated in adults and children.
CANONICA, GIORGIO +3 more
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Canadian Allergy & Immunology Today, 2021
Food allergy affects approximately 7% of the Canadian population and is a lifelong diagnosis for many patients. While fatal anaphylaxis is rare, accidental exposures are common, with many accidental reactions being moderate- to-severe. The fear of severe or fatal anaphylaxis is of major concern and food allergy represents a significant burden on the ...
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Food allergy affects approximately 7% of the Canadian population and is a lifelong diagnosis for many patients. While fatal anaphylaxis is rare, accidental exposures are common, with many accidental reactions being moderate- to-severe. The fear of severe or fatal anaphylaxis is of major concern and food allergy represents a significant burden on the ...
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Current Opinion in Allergy & Clinical Immunology, 2012
Egg allergy is one of the most common food allergies of childhood and no interventional therapy is currently approved by the Food and Drug Administration. Much recent research has focused on the safety, efficacy, and mechanism of oral immunotherapy (OIT) as a disease-modifying treatment.Small pilot studies with varying protocol designs have shown egg ...
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Egg allergy is one of the most common food allergies of childhood and no interventional therapy is currently approved by the Food and Drug Administration. Much recent research has focused on the safety, efficacy, and mechanism of oral immunotherapy (OIT) as a disease-modifying treatment.Small pilot studies with varying protocol designs have shown egg ...
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Oral immunotherapy for food allergy
Current Allergy and Asthma Reports, 2009Food allergy is an increasingly prevalent disorder with potentially life-threatening complications that requires life-altering changes in dietary habits and psychosocial interactions. The standard of care presently includes strict dietary elimination of the implicated allergen and ready access to injectable epinephrine; however, no active, definitive ...
Amy M, Scurlock +2 more
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Oral Immunotherapy for Allergic Conjunctivitis
Cornea, 2014Antigen-specific immunotherapy is expected to be a desirable treatment for allergic diseases. Currently, antigen-specific immunotherapy is performed by administering disease-causing antigens subcutaneously or sublingually. These approaches induce long-term remission in patients with allergic rhinitis or asthma.
Waka, Ishida +4 more
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Oral immunotherapy for peanut allergy
BMJ, 2010A potentially important advance, but long term effectiveness and safety need to be ...
Aziz, Sheikh +2 more
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Oral immunotherapy for food allergy
Current Opinion in Pediatrics, 2010Food allergy is a difficult clinical problem for which no disease-modifying therapy currently exists.The daily administration of graded allergen doses through oral immunotherapy (OIT) is one promising experimental approach to the development of a clinically available treatment.
Brian P, Vickery, Wesley, Burks
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Oral Immunotherapy for Peanut Allergy
Annual Review of Medicine, 2016Peanut allergy is a common disease and the cause of severe, life-threatening allergic reactions and death. It is rarely outgrown; most pediatric patients carry the disease into adulthood. Peanut allergy poses a significant burden on the quality of life of sufferers and their families, which results mainly from the fear of accidental peanut ingestion ...
Katherine, Anagnostou, Andrew, Clark
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Oral Immunotherapy for Food Allergy
Immunology and Allergy Clinics of North America, 2016Food allergy is a potentially life-threatening condition with no approved therapies, apart from avoidance and injectable epinephrine for acute allergic reactions. Oral immunotherapy (OIT) is an experimental treatment in which food-allergic patients consume gradually increasing quantities of the food to increase their threshold for allergic reaction ...
Allison J, Burbank +3 more
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