Results 31 to 40 of about 138,961 (205)
Oral Immunotherapy for Food Allergies [PDF]
Annals of Nutrition and Metabolism, 2016 Oral immunotherapy (OIT) is a promising investigational therapy for food allergy. Clinical trials in peanut, milk, egg, and wheat allergy provide evidence that OIT can effectively desensitize a majority of individuals to a food allergen. While a portion of subjects demonstrate sustained unresponsiveness, the majority regain sensitivity with allergen ...
Elizabeth, Feuille, Anna, Nowak-Węgrzyn
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Oral Immunotherapy for Food Allergy [PDF]
Journal of Investigational Allergology and Clinical Immunology, 2017 Food allergy is a potentially life-threatening condition with no approved therapies apart from avoidance and injectable epinephrine for treatment of acute allergic reactions. Oral immunotherapy (OIT) is an experimental treatment in which patients consume gradually increasing quantities of the food to which they are allergic in an attempt to induce some
Deborah M Hussey, Freeland +5 more
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Implementation of anaphylaxis management guidelines [PDF]
, 2012 Anaphylaxis management guidelines recommend the use of intramuscular adrenaline in severe reactions, complemented by antihistamines and corticoids; secondary prevention includes allergen avoidance and provision of self-applicable first aid drugs.
Gough, Hannah +12 more
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Effect of Oral Immunotherapy on Nasal Blockage in Experimental Allergic Rhinitis
Journal of Pharmacological Sciences, 2005 We previously reported that when Japanese cedar pollen was prophylactically p.o. administered before a sensitization stage in a guinea-pig model of allergic rhinitis, pollen-induced nasal blockage was suppressed.
Takeshi Nabe +4 more
doaj +1 more source
Immune mechanisms of oral immunotherapy [PDF]
Journal of Allergy and Clinical Immunology, 2018 Oral immunotherapy (OIT) has demonstrated reproducibly successful desensitization in patients with food allergy completing clinical trials and, in some studies, sustained unresponsiveness. These clinical outcomes have been associated with characteristic modifications in the allergen-specific immune response, but a detailed synthesis of OIT's mechanisms
Michael D, Kulis +3 more
openaire +2 more sources
Immunity, Inflammation and Disease, 2022 Backgound Cow's milk allergy (CMA) is the most common allergy in infants that decreases the quality of life of patients and their families. Standard treatment for CMA is the strict avoidance of milk; new treatment strategies such as oral immunotherapy ...
Lujing Tang +3 more
doaj +1 more source
Cochrane acute respiratory infections group's stakeholder engagement project identified systematic review priority areas [PDF]
, 2018 Objective: Cochrane acute respiratory infections (ARIs) group conducts systematic reviews of the evidence for treatment and prevention of ARIs. We report the results of a prioritization project, aiming to identify highest priority systematic review ...
Clark, Justin +5 more
core +1 more source
New modalities of allergen immunotherapy
Human Vaccines & Immunotherapeutics, 2018 Allergen immunotherapy is a rapidly evolving field. Although subcutaneous immunotherapy has been practiced for over a hundred years, improved understanding of the underlying immunological mechanisms has led to the development of new, efficacious and ...
Manish Ramesh, Merhunisa Karagic
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The Role of Palliative Surgery for Malignant Bowel Obstruction and Perforation in Advanced Microsatellite Instability-High Colorectal Carcinoma in the Era of Immunotherapy: Case Report. [PDF]
, 2020 The role of palliative surgery in the management of acute complications in patients with disseminated malignancy remains controversial given the complexity of assessing acute surgical risk and long-term oncologic outcome. With the emergence of checkpoint
Bold, Richard J +13 more
core
The gut microbiota and immune checkpoint inhibitors. [PDF]
, 2018 Although immunotherapy has been remarkably effective across multiple cancer types, there continues to be a significant number of non-responding patients. A possible factor proposed to influence the efficacy of immunotherapies is the gut microbiome.
Daud, Adil, Humphries, Audrey
core +1 more source