Results 61 to 70 of about 2,166,017 (392)

Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer. [PDF]

, 2017
INTRODUCTION: Colorectal cancer remains the second leading cause of cancer death in the United States, and new strategies to prevent, detect, and treat the disease are needed.
Aka, Allison A., Pattison, Amanda M., Rappaport, Jeff A., Sato, Takami, Snook, Adam E., Waldman, Scott A.   +5 more
core   +2 more sources

Alopecia areata: a multifactorial autoimmune condition [PDF]

, 2019
Alopecia areata is an autoimmune disease that results in non-scarring hair loss, and it is clinically characterised by small patches of baldness on the scalp and/or around the body. It can later progress to total loss of scalp hair (Alopecia totalis) and/
Butcher, John P., Henriquez, Fiona L., Reid, Stuart, Simakou, Teontor   +3 more
core   +1 more source

Allergen‐specific B cell responses in oral immunotherapy‐induced desensitization, remission, and natural outgrowth in cow's milk allergy

Allergy. European Journal of Allergy and Clinical Immunology
Antigen‐specific memory B cells play a key role in the induction of desensitization and remission to food allergens in oral immunotherapy and in the development of natural tolerance (NT).
P. Satitsuksanoa, W. van de Veen, G. Tan, Juan-Felipe Lopez, O. Wirz, Kirstin Jansen, M. Sokolowska, David Mirer, Anna Głobińska, T. Boonpiyathad, S. Schneider, Elena Barletta, Hergen Spits, Iris Chang, H. Babayev, İlhan Tahralı, Gunnur Deniz, E. Yücel, A. Kıykım, Scott D Boyd, C. Akdis, K. Nadeau, M. Akdiş   +22 more
semanticscholar   +1 more source

Clinical and histopathological features of the first known case of glycogenic acanthosis resembling an isolated gingival tumour: A case report

Oral and Maxillofacial Surgery Cases
Glycogenic acanthosis is a common benign lesion of the oesophagus. However, extra-oesophageal localisations in the larynx and oral mucosa in the form of white, papular or plaque-like lesions are possible.
Svyat Strokov, Anne-Laure Ejeil, Hélène Raybaud, Christine Voha, Sophie-Myriam Dridi   +4 more
doaj   +1 more source

Metronomic Chemotherapy with Vinorelbine Produces Clinical Benefit and Low Toxicity in Frail Elderly Patients Affected by Advanced Non-Small Cell Lung Cancer [PDF]

, 2018
Lung cancer is the leading cause of death worldwide. The treatment choice for advanced stage of lung cancer may depend on histotype, performance status (PS), age, and comorbidities. In the present study, we focused on the effect of metronomic vinorelbine
Bruno, P, D'Ascanio, M, Fiorentino, C, Grieco, A, Mancini, R, Pezzuto, A, Ricci, A, Sposato, B   +7 more
core   +1 more source

Two‐year post‐treatment outcomes following peanut oral immunotherapy in the Probiotic and Peanut Oral Immunotherapy‐003 Long‐Term (PPOIT‐003LT) study

Allergy. European Journal of Allergy and Clinical Immunology
Few studies have examined long‐term outcomes following oral immunotherapy (OIT); none have examined long‐term risks and benefits associated with distinct clinical outcomes (desensitization, remission).
P. Loke, Xiaofang Wang, Melanie Lloyd, S. Ashley, Adriana C Lozinsky, Michael Gold, Michael D O'Sullivan, Patrick Quinn, M. Robinson, A. D. Galvin, Francesca Orsini, M. Tang   +11 more
semanticscholar   +1 more source

CSACI guidelines for the ethical, evidence-based and patient-oriented clinical practice of oral immunotherapy in IgE-mediated food allergy

Allergy, Asthma & Clinical Immunology, 2020
Background Oral immunotherapy (OIT) is an emerging approach to the treatment of patients with IgE-mediated food allergy and is in the process of transitioning to clinical practice.
P. Bégin, E. Chan, H. Kim, M. Wagner, M. Cellier, C. Favron-Godbout, E. Abrams, M. Ben-Shoshan, S. Cameron, S. Carr, D. Fischer, A. Haynes, S. Kapur, M. Primeau, J. Upton, T. V. Vander Leek, M. Goetghebeur   +16 more
semanticscholar   +1 more source

Omalizumab effectiveness in patients with a previously failed oral immunotherapy for severe milk allergy

Immunity, Inflammation and Disease, 2021
Some studies addressed the issue of omalizumab (OML) effectiveness in children starting their first oral immunotherapy (OIT) attempt but no study investigated the possible role of OML in the setting of patients with persisting milk allergy after a failed
L. Badina, Beatrice Belluzzi, Sarah Contorno, Benedetta Bossini, E. Benelli, E. Barbi, I. Berti   +6 more
semanticscholar   +1 more source

Evaluation of peripheral basophil activation during exercise provocation test for desensitized patients

Frontiers in Allergy, 2023
Some food allergic patients who have undergone oral immunotherapy develop exercise-induced allergic reactions on desensitization (EIARDs). This study investigated basophil activation status during the exercise provocation test (EPT) performed to diagnose
Jun Kunizaki, Jun Kunizaki, Shiro Sugiura, Akira Sakai, Akira Sakai, Miyuki Teshigawara, Atsushi Makino, Yoshihiro Takasato, Teruaki Matsui, Yasuto Kondo, Komei Ito   +10 more
doaj   +1 more source

Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort. [PDF]

, 2016
Purpose Treatment with pembrolizumab, an anti-programmed death-1 antibody, at 10 mg/kg administered once every 2 weeks, displayed durable antitumor activity in programmed death-ligand 1 (PD-L1) -positive recurrent and/or metastatic (R/M) head and neck ...
Berger, Raanan, Burtness, Barbara, Cheng, Jonathan D, Chow, Laura QM, Chung, Hyun Cheol, Dolled-Filhart, Marisa, Eder, Joseph Paul, Geva, Ravit, Gupta, Shilpa, Haddad, Robert, Kang, Hyunseok, Keam, Bhumsuk, Lee, Se-Hoon, Lin, Chia-Chi, Mahipal, Amit, Mehra, Ranee, Meister, Amy, Muro, Kei, Pathiraja, Kumudu, Seiwert, Tanguy Y, Tahara, Makoto, Weiss, Jared   +21 more
core   +2 more sources