Oral Immunotherapy (OIT): A Personalized Medicine [PDF]
Oral Immunotherapy (OIT), a promising allergen-specific approach in the management of Food Allergies (FA), is based on the administration of increasing doses of the culprit food until reaching a maintenance dose.
Francesca Mori +3 more
doaj +2 more sources
Bronchial hyperresponsiveness and asthma during oral immunotherapy for egg or peanut allergy in children [PDF]
Background Bronchial hyperresponsiveness (BHR) and asthma are frequently present in children with food allergy. We assessed BHR in children receiving oral immunotherapy (OIT) for persistent egg or peanut allergy and examined whether OIT affects asthma ...
Janne Burman +6 more
doaj +2 more sources
Home-Based Peanut Oral Immunotherapy for Low-Risk Peanut-Allergic Preschoolers During the COVID-19 Pandemic and Beyond [PDF]
The coronavirus disease 2019 (COVID-19) pandemic has led to the deprioritization of non-emergency services, such as oral food challenges and the initiation of oral immunotherapy (OIT) for food-allergic children.
Gilbert T. Chua +8 more
doaj +3 more sources
Therapeutic perspectives in food allergy [PDF]
Background In the last twenty years, several studies have been conducted in the search for new therapeutic strategies in patients with food allergy; in particular, after the failure of injection immunotherapy, three different routes of administration ...
Francesco Marcucci +4 more
doaj +3 more sources
Hazelnut oral immunotherapy in children: An Italian single-center retrospective cohort study. [PDF]
Abstract Introduction Hazelnut oral immunotherapy (H‐OIT) is a promising treatment for hazelnut allergy (HA). The aim of this study was to assess the safety and efficacy of H‐OIT in a pediatric population, while describing its clinical and allergy characteristics. Methods Children undergoing H‐OIT at our tertiary pediatric hospital Allergy Unit between
Barni S +9 more
europepmc +2 more sources
Wheat allergy, a new and emerging threat of food allergy for children. [PDF]
Abstract Compared to cow's milk, eggs and peanut, knowledge on wheat allergy is limited. During the past 2 decades, IgE‐mediated wheat allergy in children has been frequently observed all over the World, especially in Asia. Wheat allergy usually presents in infants between 6 and 12 months of age.
Vichyanond P +4 more
europepmc +2 more sources
Variation in pediatric egg and milk allergy management: A multinational survey in Ireland, Spain, and Canada. [PDF]
Pediatric Allergy and Immunology, Volume 37, Issue 2, February 2026.
Gallagher A +6 more
europepmc +2 more sources
Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapy (PPOIT) in inducing desensitisation or tolerance in children with peanut allergy compared with oral immunotherapy (OIT) alone and with placebo (the PPOIT-003 study) [PDF]
Introduction Peanut allergy is the the most common cause of life-threatening food-induced anaphylaxis. There is currently no effective long-term treatment.
+25 more
doaj +2 more sources
Life‐threatening anaphylaxis in children with cow's milk allergy during oral immunotherapy and after treatment failure [PDF]
Background Oral immunotherapy (OIT) is a promising therapeutic approach for children with persistent IgE‐mediated cow's milk allergy (CMA) but data are still limited.
Laura Badina +5 more
doaj +2 more sources
Safety and Efficacy of Very Low-Dose Multi-Nut Oral Immunotherapy in Children. [PDF]
ABSTRACT Background Oral immunotherapy (OIT) is a management strategy for food allergies, typically one at a time, with maintenance doses ≥ 300 mg protein. However, 30% of allergic children have multiple trigger foods, and large maintenance doses are associated with side effects. If efficacious, Very Low‐Dose OIT (VLOIT) may enhance safety in multi‐OIT.
Upton JEM +17 more
europepmc +2 more sources

