Results 21 to 30 of about 2,548 (213)

The Efficacy of a New Protocol of Oral Immunotherapy to Wheat for Desensitization and Induction of Tolerance

Iranian Journal of Allergy, Asthma and Immunology, 2022
Oral immunotherapy (OIT) is a novel approach to desensitization and tolerance induction in food allergy patients. This study aimed to design and implement a new wheat OIT protocol, evaluate its efficacy in tolerance induction, and assess specific ...
Samin Sharafian, Aliakbar Amirzargar, Mohammad Gharagozlou, Nima Parvaneh, Mansoureh Shariat, Marzieh Tavakol, Masoud Movahedi   +6 more
doaj   +1 more source

Oral Immunotherapy for Children with Cow’s Milk Allergy

Pathogens, 2021
Cow’s milk allergy (CMA) is one of the most common IgE-dependent food allergies in children. Some children develop severe and persistent CMA, with near-fatal reactions after exposure to trace amounts of cow’s milk (CM).
Mika Ogata, Jun Kido, Kimitoshi Nakamura
doaj   +1 more source

Side effects and their impact on the success of milk oral immunotherapy (OIT) in children. [PDF]

Int J Immunopathol Pharmacol, 2017
Oral immunotherapy (OIT) has been introduced as a new immune-modulating treatment under investigation for food allergies. The aim of our study was to evaluate the success of OIT in a cohort of children with milk allergy. These children underwent OIT in a clinical practice and were followed for up to ten years.
Mori F, Cianferoni A, Brambilla A, Barni S, Sarti L, Pucci N, de Martino M, Novembre E.   +7 more
europepmc   +5 more sources

Abatacept to induce remission of peanut allergy during oral immunotherapy (ATARI): protocol for a phase 2a randomized controlled trial

Frontiers in Medicine, 2023
ContextWhile oral immunotherapy (OIT) has been shown to promote the remission of mild peanut allergy in young children, there is still an unmet need for a disease-modifying intervention for older patients and those with severe diseases.
Camille Braun, Camille Braun, Camille Braun, Pauline Azzano, Florence Gingras-Lessard, Émilie Roy, Kathryn Samaan, François Graham, François Graham, Louis Paradis, Louis Paradis, Anne Des Roches, Philippe Bégin, Philippe Bégin   +13 more
doaj   +1 more source

A Review of Shared Decision-Making, Published Protocols, and Post-desensitization Strategies in Oral Immunotherapy (OIT). [PDF]

Curr Allergy Asthma Rep
Abstract Purpose of Review The aim of this review is to highlight key published oral immunotherapy (OIT) protocols and post-desensitization strategies for the major food allergens and to cover important concepts to consider when evaluating OIT for food-allergic patients.
Laubach S, Kim EH, Greenhawt M, Bailey S, Anagnostou A.   +4 more
europepmc   +5 more sources

Oral immunotherapy for food allergy: Translation from studies to clinical practice?

World Allergy Organization Journal, 2023
Oral immunotherapy (OIT) is now recognized as an alternative active treatment to strict food avoidance in certain patients with IgE-mediated food allergy. Studies have confirmed the efficacy of OIT to desensitize children with allergy to cow's milk, eggs,
Guillaume Pouessel, MD, Guillaume Lezmi, MD, PhD   +1 more
doaj   +1 more source

CD8+ T cell differentiation status correlates with the feasibility of sustained unresponsiveness following oral immunotherapy

Nature Communications, 2022
Oral immunotherapy (OIT) clinical trials have helped a subset of participants achieve sustained unresponsiveness (SU) to the cognate allergen. Here the authors analyse immune cells from participants from one peanut OIT trial and show that CD8+ T cell ...
Abhinav Kaushik, Diane Dunham, Xiaorui Han, Evan Do, Sandra Andorf, Sheena Gupta, Andrea Fernandes, Laurie Elizabeth Kost, Sayantani B. Sindher, Wong Yu, Mindy Tsai, Robert Tibshirani, Scott D. Boyd, Manisha Desai, Holden T. Maecker, Stephen J. Galli, R. Sharon Chinthrajah, Rosemarie H. DeKruyff, Monali Manohar, Kari C. Nadeau   +19 more
doaj   +1 more source

Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis [PDF]

, 2017
Background: The European Academy of Allergy and Clinical Immunology (EAACI) is developing Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated Food Allergy.
Dhami, Sangeeta, et al, Nurmatov, Ulugbek   +2 more
core   +9 more sources

High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy

Cell Reports Medicine, 2021
Summary: Peanut allergy can result in life-threatening reactions and is a major public health concern. Oral immunotherapy (OIT) induces desensitization to food allergens through administration of increasing amounts of allergen. To dissect peanut-specific
Genghao Chen, Ellen L. Shrock, Mamie Z. Li, Jonathan M. Spergel, Kari C. Nadeau, Jacqueline A. Pongracic, Dale T. Umetsu, Rima Rachid, Andrew J. MacGinnitie, Wanda Phipatanakul, Lynda Schneider, Hans C. Oettgen, Stephen J. Elledge   +12 more
doaj   +1 more source

Oral Immunotherapy for Food Allergy: Towards a New Horizon [PDF]

, 2013
Food allergy has increased dramatically in prevalence over the past decade in westernized countries, and is now a major public health problem. Unfortunately for patients with food allergy, there is no effective therapy beyond food allergen avoidance, and
Khoriaty, Evelyne Nassim, Umetsu, Dale T.   +1 more
core   +1 more source