Results 71 to 80 of about 2,548 (213)

A Randomized, Open-Label Trial of Hen's Egg Oral Immunotherapy : Efficacy and Humoral Immune Responses in 50 Children [PDF]

, 2021
BACKGROUND: Egg allergy is the second most common food allergy in children. Persistent food allergy increases the risk of anaphylaxis and reduces the quality of life.
Alenius, Harri, Fyhrquist, Nanna, Karisola, Piia, Mäkelä, Mika J., Palosuo, Kati, Savinko, Terhi   +5 more
core   +1 more source

Codfish Oral Immunotherapy in Children Aged 2–10: Randomized Placebo‐Controlled Study

Allergy, EarlyView.
Codfish OIT significantly increased desensitization in children with fish allergy (43% vs. 11% placebo, p = 0.003), with 69% achieving 10‐fold threshold increases versus 26% in placebo (p = 0.0003). Sustained unresponsiveness remained limited (23% vs. 9%, p = 0.332). Treatment demonstrated acceptable safety with predominantly mild reactions and reduced
Agnes Sze‐yin Leung, Yanjun Gu, Ann Wing‐shan Au, Rosetta Tsz‐ching Leung, Vanessa Hiu‐tung Tang, Kin Yi Fung, Janice Min Li, Christine Yee‐yan Wai, Ting Fan Leung, Gary Wing‐kin Wong   +9 more
wiley   +1 more source

Diagnosis of Eosinophilic Esophagitis in an Infant Undergoing Milk Oral Immunotherapy - A Case Report [PDF]

, 2014
Although the standard of care for cow’s milk (CM) allergy is strict food avoidance, oral immunotherapy (OIT) is being widely investigated as an alternative management option in certain cases.
Antunes, J, Chambel, M, Leiria-Pinto, P, Morais Silva, P, Prates, S   +4 more
core  

FAST: Towards safe and effective subcutaneous immunotherapy of persistent life-threatening food allergies. [PDF]

, 2012
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field.ABSTRACT: The FAST project (Food Allergy Specific Immunotherapy) aims at the development of safe and effective treatment of food allergies ...
A Bonura, A Bugajska-Schretter, A Nowak-Wegrzyn, A Nowak-Wegrzyn, BE Garcia, E Enrique, E Enrique, E Sten, EA Pastorello, EH Kim, EN Mills, G Garcia-Casado, G Pauli, G Pauli, G Salcedo, G Senti, GA Bannon, H Lemon-Mule, H Plewako, HS Nelson, I Swoboda, I Swoboda, JJ Oppenheimer, KM Jarvinen, KM Jarvinen, KT Nouri-Aria, L Tordesillas, L Zuidmeer, L Zuidmeer, LF Pacios, M Fernandez-Rivas, M Fernandez-Rivas, M Jutel, M Mempel, M Toda, MP Ross, R Kerzl, RJ Rona, TK Hansen, V Schulten, XF Wang, XM Li   +41 more
core   +3 more sources

Oral immunotherapy for food allergy in children: is it worth it? [PDF]

, 2022
Introduction: Oral immunotherapy (OIT) is effective at inducing desensitization in food-allergic individuals, and is a valid therapeutic option for those allergic to peanut, cow’s milk and egg. However, there is a high rate of dose-related adverse events,
Nagendran, S, Patel, N, Turner, P
core   +1 more source

Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study

Immunology, EarlyView.
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan, Karen Cerosaletti, James A. Perry, George DuToit, Monali Manohar, Hua Ling, Justin E. Paschall, Srinath Sanda, R. Sharon Chinthrajah, Gerald T. Nepom, Kari C. Nadeau, Stacie M. Jones, Gideon Lack, Ingo Ruczinski, Rasika A. Mathias   +14 more
wiley   +1 more source

Use of Immunotherapy in the Treatment of Peanut Allergies in the Pediatric Population [PDF]

, 2015
Peanut allergies are a serious issue that must be monitored and treated effectively to avoid severe adverse effects and death. In the last decade, their incidence has increased significantly, due to indeterminate factors.
Rauscher, Bethany
core  

Gut microbiota as target for innovative strategies against food allergy. [PDF]

, 2019
The dramatic increase in food allergy prevalence and severity globally requires effective strategies. Food allergy derives from a defect in immune tolerance mechanisms.
Berni, Canani, Bruno, C, Buono, A, Della Gatta, G, Di Scala, C, Ercolini, D., Maddalena, Y, Nocerino, R, Paparo, L, Voto, L   +9 more
core   +1 more source

Discovery of Lomitapide as a Novel Mast Cell Regulatory Agent Through Chemical Library Screening

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Chemical library screening identified lomitapide as a novel mast cell (MC) regulatory agent. Lomitapide selectively inhibits IgE/Ag‐ or phorbol 12‐myristate 13‐acetate (PMA)/ionomycin‐mediated MC degranulation by altering plasma membrane dynamics, including endocytosis and membrane fusion. ABSTRACT Allergic diseases are a global health concern, and new
Shiori Mamorita, Atsushi Furukawa, Yuka Nagata, Ryo Suzuki   +3 more
wiley   +1 more source

Combined immunodeficiency and hypoglycemia associated with mutations in hypoxia upregulated 1 [PDF]

, 2017
Non peer ...
Eriksson-Rosenberg, Ove, Fogarty, Christopher, Haapaniemi, Emma M., Hautala, Timo, Ilander, Mette, Jokitalo, Eija, Katayama, Shintaro, Kere, Juha, Keskitalo, Salla, Krjutskov, Kaarel, Lehto, Markku, Mustjoki, Satu, Seppanen, Mikko, Varjosalo, Markku, Velagapudi, Vidya, Vihinen, Helena   +15 more
core   +1 more source