The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander +3 more
wiley +1 more source
Immunotherapeutic allogeneic dendritic cell and autologous tumor cell fusion vaccine alone or combined with radiotherapy in canine oral malignant melanoma is safe and potentially effective. [PDF]
Xia YY +7 more
europepmc +1 more source
Emerging evidence suggests that periodontal health is not simply the absence of disease, but the result of a dynamic interaction between biological resilience, healthy lifestyles, adaptive coping mechanisms, and supportive environments. This results in a strong sense of coherence, which is not only a psychological state but also a biological state ...
Bruno G. Loos +4 more
wiley +1 more source
Limited Clinical Efficacy with Potential Adverse Events in a Pilot Study of Autologous Adoptive Cell Therapy in Canine Oral Malignant Melanoma. [PDF]
Xia YY, Chi KH, Liao AT, Lee JJ.
europepmc +1 more source
ABSTRACT Objective Many countries have implemented health technology assessment of their public medical insurance programs owing to rising social security costs from ageing populations and expensive emerging medical technologies. Clarifying factors that affect health utility scores is essential for implementing treatments that reflect social values ...
Masashi Sasaki +7 more
wiley +1 more source
Investigation of Oncogenic Gene Mutation and Associated Protein Expression in Ameloblastic Carcinoma
ABSTRACT Objective This study aimed to investigate gene mutations in ameloblastic carcinoma (AC) including BRAF, KRAS, and PIK3CA, along with associated protein expressions of BRAF V600E, p‐ERK1/2, and p‐mTOR, which represent activation of MAPK/ERK and PI3K/mTOR pathways, respectively.
Puangwan Lapthanasupkul +4 more
wiley +1 more source
The prognostic significance of sentinel lymph node biopsy in malignant melanoma [PDF]
Liszkay Gabriella
core
Biomarkers Correlating With the Development of Oral Squamous Cell Carcinoma From Leukoplakia
ABSTRACT Background We assessed protein biomarkers expressed in oral leukoplakia (OL) that are associated with the risk of transformation into oral squamous cell carcinoma (OSCC). Methods Tissue sections of OL transforming into OSCC (leuko‐ca), the corresponding OSCC and OL that did not progress to OSCC (leuko‐nonca) were analyzed with global relative ...
Daniel Giglio +8 more
wiley +1 more source
Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors. [PDF]
Igase M +16 more
europepmc +1 more source
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad +6 more
wiley +1 more source

