Single institution study of the immune landscape for canine oral melanoma based on transcriptome analysis of the primary tumor [PDF]
Frontiers in Veterinary Science, 2023 IntroductionUnderstanding a tumor’s immune context is paramount in the fight against cancer. Oral melanoma in dogs serves as an excellent translational model for human immunotherapy.
Isabelle F. Vanhaezebrouck +5 more
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Prognostic Factors for the Efficiency of Radiation Therapy in Dogs with Oral Melanoma: A Pilot Study of Hypoxia in Intraosseous Lesions [PDF]
Veterinary Sciences, 2022 Unresectable oral melanoma is often treated with radiation therapy (RT) and may show a temporary response to therapy. The clinical stage is one of the well-known prognostic factors for canine oral melanoma.
Shunsuke Noguchi +4 more
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Molecular and Immunohistochemical Expression of LTA4H and FXR1 in Canine Oral Melanoma [PDF]
Frontiers in Veterinary Science, 2021 Oral melanoma is a common canine tumor whose prognosis is considered ominous, but poorly predicted by histology alone. In the present study the gene and protein expression of Leukotriene A4 hydrolase (LTA4H) and Fragile-X-mental retardation-related ...
Laura Nordio +8 more
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Evaluation of Cytokine Profile in Canine Malignant Oral Melanoma [PDF]
Veterinary SciencesTen dogs with oral malignant melanoma were evaluated and treated with surgery, of which four dogs were diagnosed with melanotic melanoma and six were diagnosed with amelanotic melanoma.
Carmen G. Pérez-Santana +7 more
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Canine Oral Melanoma: Questioning the Existing Information through a Series of Clinical Cases [PDF]
Veterinary SciencesTwelve dogs with oral malignant melanomas (MM) were evaluated in this study, with demographic details indicating a balanced distribution of gender, age, and weight among various breeds.
Carmen G. Pérez-Santana +4 more
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Application of Palliative Hemostatic Radiotherapy in Canine Unresectable Oral Melanoma: A Case Report [PDF]
AnimalsA 9-year-old castrated male Schnauzer dog, weighing 11.6 kg, presented with a persistent hemorrhagic oral mass. An oral examination revealed a right maxillary oral mass characterized by continuous bleeding, halitosis, and severe pain.
Myounghun Kim +6 more
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Clinical impact of butterbur shoot extract in dogs with oral melanoma: a combined phase 1 and 2 clinical trial [PDF]
BMC Veterinary ResearchBackground Oral melanoma is one of the most devastating cancers in dogs. We previously developed a novel agent extracted from Japanese butterbur shoots and its petasin derivatives demonstrated anti-proliferative activity in canine oral melanoma cells ...
Shunsuke Noguchi +4 more
doaj +2 more sources
Journal of Indian Academy of Oral Medicine and Radiology, 2021 Malignant melanoma arises from melanocytic cells. Oral mucosal melanoma is a rare malignancy with the tendency to metastasize and locally invade tissues more readily than other malignant tumors of the oral cavity.
Jigna S Shah +2 more
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Primary melanoma of oral mucosa: A case report and review of literature
Dental Research Journal, 2012 Primary oral melanoma is a rare neoplasm of melanocytic origin, accounting for 0.5% of all oral malignancies. The "chameleonic" presentation of a mainly asymptomatic condition, rarity of this lesion, poor prognosis, and the necessity of a highly ...
Raman Preet Kaur Bhullar +5 more
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Primary malignant melanoma of oral cavity: A report of three rare cases
Contemporary Clinical Dentistry, 2016 Oral malignant melanoma (OMM) is a rare tumor of melanocytic origin, accounting for 20–30% of malignant melanomas at the mucosal surface and 16% intra-orally. Hard palate and maxillary gingiva are the most common involved sites.
Hanspal Singh +4 more
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