TP63 is implicated in apoptotic dysregulation in melanoma [PDF]
, 2010 PhDCutaneous melanoma is an aggressive malignancy accounting for 4% of skin cancers but 80% of all skin-cancer related deaths. Its incidence is rapidly rising and advanced disease is notoriously treatment-resistant.
Matin, Rubeta N H
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A randomised trial evaluating Bevacizumab as adjuvant therapy following resection of AJCC stage IIB, IIC and III cutaneous melanoma : an update [PDF]
, 2008 At present, there are no standard therapies for the adjuvant treatment of malignant melanoma. Patients with primary tumours with a high-Breslow thickness (stages IIB and IIC) or with resected loco-regional nodal disease (stage III) are at high risk of ...
Middleton, M. (Mark) +15 more
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Clinicopathological and prognostic value of Ki-67 expression in oral malignant melanoma: A systematic review and meta-analysis [PDF]
Journal of Dental Research, Dental Clinics, Dental Prospects, 2022 Background. Ki-67 is one of the new biological markers with clinical value in the pathology and prognosis of oral melanoma. It is a nuclear protein involved in regulating cell proliferation.
Mohammad Hossein Moltajaei +3 more
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Inhibitory Effects of a Reengineered Anthrax Toxin on Canine Oral Mucosal Melanomas
Toxins, 2020 Canine oral mucosal melanomas (OMM) are the most common oral malignancy in dogs and few treatments are available. Thus, new treatment modalities are needed for this disease.
Adriana Tomoko Nishiya +13 more
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Oral Malignant Melanoma: A Case Report
Prague Medical Report, 2021 Melanoma is a malignant neoplasm of the epidermal melanocytes. Awareness and early recognition of pigmented lesion inside oral cavity helps in initial diagnosis and further investigation and treatment.
Suman Sen +4 more
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Phase 1 study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers [PDF]
, 2004 We assessed the safety, tolerability and efficacy of the immunomodulatory drug, CC-5013 (REVIMID(TM)), in the treatment of patients with metastatic malignant melanoma and other advanced cancers.
Muller, G.W. +35 more
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Advances in Understanding Spontaneously Occurring Melanoma in Animals
Veterinary Sciences, 2023 Melanoma is a tumour that arises from the uncontrolled proliferation of melanocytes (pigment-producing cells) found in the skin (cutaneous melanoma and digital melanoma), mucosal surfaces (oral melanoma), and the eye (ocular melanoma) [...]
Kelly L. Blacklock +1 more
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COX-2 Silencing in Canine Malignant Melanoma Inhibits Malignant Behaviour
Frontiers in Veterinary Science, 2021 Metastatic melanoma is a very aggressive form of cancer in both humans and dogs. Dogs primarily develop oral melanoma of mucosal origin. Although oral melanoma in humans is rare, both diseases are highly aggressive with frequent metastases.
Tatiany L. Silveira +8 more
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Melanoma metastasis to the oral cavity: a rare case report and literature review [PDF]
Journal of Clinical and Investigative Surgery, 2022 About 1% of oral cancers are metastases of primary tumors from other parts of the body. The most common primary tumors that metastasize to the oral cavity are placed in the lungs, kidneys, liver and prostate for men, while in women they are placed in the
Sandra Baranovic, Aleksandar Milenovic
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Proton beam radiotherapy in the management of uveal melanoma: clinical experience in Scotland [PDF]
, 2008 <p>Aim: To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland.</p> <p>Methods: A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994–2005).
McConnachie, A. +9 more
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