Results 71 to 80 of about 82,354 (210)

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Primary mucosal melanoma: A case report

Journal of Craniomaxillofacial Research, 2017
Malignant melanoma is an aggressive malignancy of melanocytes affecting both skin and mucosa. Primary oral melanoma occurs 0.2-8% of all melanomas and accounts for 0.5% of all oral malignancies.
Fereshteh Baghai, Sedigheh Rahrotaban, Ata Garajei, Fatemeh Pirzadeh, Samira Derakhshan   +4 more
doaj  

Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma. [PDF]

Int J Mol Sci, 2023
Usta SZ, Uchihashi T, Kodama S, Kurioka K, Inubushi T, Shimooka T, Sugauchi A, Seki S, Tanaka S.   +8 more
europepmc   +1 more source

A scalable workflow for sensitive detection and genomic profiling of tumour cells in lymph nodes from FFPE tissue

The Journal of Pathology, EarlyView.
Abstract Accurate detection of lymph node (LN) metastases is critical for prognosis and surgical decision‐making in head and neck squamous cell carcinoma (HNSCC) and other epithelial cancers. Standard histopathology examines only a small fraction of LN tissue, limiting sensitivity for micrometastases and isolated tumour cells.
Tristan Bergmann, Marianne Hölbling, Monica Sudarsanam, Christiane Driemel, Maximilian E Daniels, Joanna Swierz, Sandra Jaschinski, Maximilian Seidl, Norbert R Kübler, Wolfram T Knoefel, Rui PL Neves, Karl C Sproll, Nikolas H Stoecklein   +12 more
wiley   +1 more source

Oral malignant melanoma of the lower jaw-a case report with immunohistochemical investigations. [PDF]

Ecancermedicalscience, 2023
Tamgadge S, Pereira T, Date A, Kalimuthu P, Tamgadge A.   +4 more
europepmc   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Amelanotic Melanoma - A case report with review of literature

Journal of Indian Academy of Oral Medicine and Radiology, 2007
Oral malignant melanoma is a rare disease. Amelanotic melanoma is a subtype of cutaneous melanoma with little or no pigmentation. True AMM are rare and there may be some pigmentation at the periphery of the lesion.
R Kamala, R Gopakumar, Subhas Babu, S Giridhar Naidu, Vidya AjiIa, Karthik Hegde   +5 more
doaj  

Primary Malignant Melanoma of the Endometrium: A Case Report

Case Reports in Oncology
Introduction: Malignant melanoma most commonly occurs in the skin. Primary malignant melanoma of endometrium is quite rare. Its diagnosis depends on clinical characteristics and pathological examination. It usually exhibits high degree of tumor histology,
Xiuting Shi, Jie Shi, Yanli Li, Xin Li, Xuemei Hu, Han Gao   +5 more
doaj   +1 more source

A Case Report of Oral Malignant Melanoma: A Silent Killer. [PDF]

Cureus, 2023
Kukde MM, Madurwar AU, Selokar DS, Noman O.   +3 more
europepmc   +1 more source