Results 21 to 30 of about 1,752,430 (254)

Microbiota in Gut, Oral Cavity, and Mitral Valves Are Associated With Rheumatic Heart Disease

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Rheumatic heart disease refers to the long-term damage of heart valves and results from an autoimmune response to group A Streptococcus infection. This study aimed to analyze the microbiota composition of patients with rheumatic heart disease and explore
Xue-Rui Shi   +19 more
doaj   +1 more source

Construction and characterization of mice with conditional knockout of Stat3 gene in microglia

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Objective·To construct mice with conditional knockout of Stat3 gene in microglia based on the Cre-Loxp system and validate their knockout efficiency.Methods·Cx3cr1creERT2 and Stat3fl/fl genotypic mice were bred for conditional knockout mice (CKO) and ...
ZHU Xiaochen   +5 more
doaj   +1 more source

Periodontitis Salivary Microbiota Aggravates Ischemic Stroke Through IL-17A

open access: yesFrontiers in Neuroscience, 2022
Although epidemiological studies suggest that periodontitis is tightly associated with ischemic stroke, its impact on ischemic stroke and the underlysing mechanisms are poorly understood.
Yan-Lin Chen   +27 more
doaj   +1 more source

A Mouse Periodontitis Model With Humanized Oral Bacterial Community

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Increasing evidence suggests that periodontitis, characterized by oral dysbiosis, is a critical player in the progression of multiple systemic diseases in humans.
Lan Bai   +12 more
doaj   +1 more source

The Oral Microbiota Changes in Orthodontic Patients and Effects on Oral Health: An Overview [PDF]

open access: yes, 2021
Nowadays, there is a considerable interest to study the biological and microbiological changes that accompany orthodontic treatment. Growing knowledge on oral microbiota allows, day after day, to identify and characterize the microbial arrangements ...
Contaldo, Maria   +15 more
core   +3 more sources

Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background NCOR1 (nuclear receptor corepressor 1) is an essential coregulator of gene transcription. It has been shown that NCOR1 in macrophages plays important roles in metabolic regulation.
Lin‐Juan Du   +15 more
doaj   +1 more source

Child saliva microbiota and caries: a randomized controlled maternal education trial in rural Uganda

open access: yesScientific Reports, 2022
Undernutrition is a public health challenge in sub-Saharan countries, including Uganda. In a previous randomized controlled trial (RCT) with a nutrition, hygiene and stimulation education intervention among mothers of 6 months’ old children, we found ...
Grace K. M. Muhoozi   +10 more
doaj   +1 more source

Assessment of bidirectional relationships between circulating cytokines and periodontitis: Insights from a mendelian randomization analysis

open access: yesFrontiers in Genetics, 2023
Background: The purpose of this Mendelian randomization (MR) study was to assess the causal relationship between circulating cytokines and periodontitis.Materials and methods: Based on the aggregated statistics of the largest publicly available genome ...
Shi-Jia Huang   +9 more
doaj   +1 more source

The oral microbiota and cardiometabolic health: A comprehensive review and emerging insights

open access: yesFrontiers in Immunology, 2022
There is mounting evidence demonstrating that oral dysbiosis causes periodontal disease and promotes the development of cardiovascular disease. The advancement of omics techniques has driven the optimization of oral microbiota species analysis and has ...
Yiwen Li   +7 more
doaj   +1 more source

Oral Microbiota and Cancer Development [PDF]

open access: yes, 2020
Oral microbiota are among the most diverse in the human body. More than 700 species have been identified in the mouth, and new sequencing methods are allowing us to discover even more species.
Rautava, Jaana   +3 more
core   +1 more source

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