Microbiota in Gut, Oral Cavity, and Mitral Valves Are Associated With Rheumatic Heart Disease
Rheumatic heart disease refers to the long-term damage of heart valves and results from an autoimmune response to group A Streptococcus infection. This study aimed to analyze the microbiota composition of patients with rheumatic heart disease and explore
Xue-Rui Shi +19 more
doaj +1 more source
Construction and characterization of mice with conditional knockout of Stat3 gene in microglia
Objective·To construct mice with conditional knockout of Stat3 gene in microglia based on the Cre-Loxp system and validate their knockout efficiency.Methods·Cx3cr1creERT2 and Stat3fl/fl genotypic mice were bred for conditional knockout mice (CKO) and ...
ZHU Xiaochen +5 more
doaj +1 more source
Periodontitis Salivary Microbiota Aggravates Ischemic Stroke Through IL-17A
Although epidemiological studies suggest that periodontitis is tightly associated with ischemic stroke, its impact on ischemic stroke and the underlysing mechanisms are poorly understood.
Yan-Lin Chen +27 more
doaj +1 more source
A Mouse Periodontitis Model With Humanized Oral Bacterial Community
Increasing evidence suggests that periodontitis, characterized by oral dysbiosis, is a critical player in the progression of multiple systemic diseases in humans.
Lan Bai +12 more
doaj +1 more source
The Oral Microbiota Changes in Orthodontic Patients and Effects on Oral Health: An Overview [PDF]
Nowadays, there is a considerable interest to study the biological and microbiological changes that accompany orthodontic treatment. Growing knowledge on oral microbiota allows, day after day, to identify and characterize the microbial arrangements ...
Contaldo, Maria +15 more
core +3 more sources
Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice
Background NCOR1 (nuclear receptor corepressor 1) is an essential coregulator of gene transcription. It has been shown that NCOR1 in macrophages plays important roles in metabolic regulation.
Lin‐Juan Du +15 more
doaj +1 more source
Child saliva microbiota and caries: a randomized controlled maternal education trial in rural Uganda
Undernutrition is a public health challenge in sub-Saharan countries, including Uganda. In a previous randomized controlled trial (RCT) with a nutrition, hygiene and stimulation education intervention among mothers of 6 months’ old children, we found ...
Grace K. M. Muhoozi +10 more
doaj +1 more source
Background: The purpose of this Mendelian randomization (MR) study was to assess the causal relationship between circulating cytokines and periodontitis.Materials and methods: Based on the aggregated statistics of the largest publicly available genome ...
Shi-Jia Huang +9 more
doaj +1 more source
The oral microbiota and cardiometabolic health: A comprehensive review and emerging insights
There is mounting evidence demonstrating that oral dysbiosis causes periodontal disease and promotes the development of cardiovascular disease. The advancement of omics techniques has driven the optimization of oral microbiota species analysis and has ...
Yiwen Li +7 more
doaj +1 more source
Oral Microbiota and Cancer Development [PDF]
Oral microbiota are among the most diverse in the human body. More than 700 species have been identified in the mouth, and new sequencing methods are allowing us to discover even more species.
Rautava, Jaana +3 more
core +1 more source

