Results 81 to 90 of about 425,021 (310)

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang   +17 more
wiley   +1 more source

Analysis of the histopathological artifacts in punch biopsies of the normal oral mucosa [PDF]

open access: yes, 2008
Objectives: To study the most frequent artifacts of punch biopsies of the healthy oral mucosa, distinguishing between those attributable to the surgical technique and those resulting from sample processing in the laboratory.
Camacho Alonso, Fabio   +3 more
core  

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

The role and potential mechanisms of prebiotics in periodontitis treatment: a review

open access: yesJournal of Functional Foods
Periodontitis is a chronic inflammatory disease induced by microbial plaque. Traditional mechanical and pharmacological therapeutic techniques have limitations.
Ke-Xin Yu   +4 more
doaj   +1 more source

Oral lichenoid lesions related to contact with dental materials: A literature review [PDF]

open access: yes, 2009
Oral lichenoid lesions related to contact are defined as oral-cavity eruptions with an identifiable etiology, and are clinically and histologically similar to oral lichen planus.
Bullon, Pedro   +4 more
core  

Dendritic cells of the oral mucosa [PDF]

open access: yesMucosal Immunology, 2014
The oral cavity contains distinct mucosal surfaces, each with its own unique distribution of dendritic cell (DC) subsets. In addition to tissue-specific properties, such organization might confer differential immune outcomes guided by tissue-resident DCs, which translate in the lymph node into an overall immune response.
openaire   +2 more sources

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

open access: yesAdvanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh   +11 more
wiley   +1 more source

Salivary pH, calcium, phosphorus and selected enzymes in healthy dogs: A pilot study [PDF]

open access: yes, 2017
Background Saliva in dogs, as in humans, is a complex fluid secreted by different salivary glands in the oral cavity to protect the oral mucosa and teeth.
Badon, Tamara   +5 more
core   +2 more sources

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

open access: yesAdvanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li   +22 more
wiley   +1 more source

Guided Biofilm Therapy for Management of “Desquamative Gingivitis”—Clinical Cases

open access: yesClinics and Practice
Background: Desquamative gingivitis is a clinical manifestation often associated with various mucocutaneous disorders, characterized by red, painful, and friable gingiva.
Blagovesta Yaneva   +3 more
doaj   +1 more source

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