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Interventions for the Prevention of Oral Mucositis in Patients Receiving Cancer Treatment: Evidence from Randomised Controlled Trials

open access: yesCurrent Oncology, 2023
Oral mucositis is a common and most debilitating complication associated with cancer therapy. Despite the significant clinical and economic impact of this condition, there is little to offer to patients with oral mucositis, and the medications used in ...
Giuseppe Colella   +10 more
doaj   +2 more sources

Management of oral mucositis caused by radiotherapy – A comprehensive review

open access: greenSRM Journal of Research in Dental Sciences, 2022
Oral cancer is the malignant neoplasm involving the oral cavity. The treatment of oral cancer is surgery, radiotherapy, and adjuvant chemotherapy. Oral mucositis is the most common side effect when radiotherapy treatment for oral cancer is indicated ...
Manisha Singh, Anjana Bagewadi
doaj   +2 more sources

Predicting Nomogram for Severe Oral Mucositis in Patients with Nasopharyngeal Carcinoma during Intensity-Modulated Radiation Therapy: A Retrospective Cohort Study

open access: yesCurrent Oncology, 2022
Background: Oral mucositis is an acute adverse reaction with high incidence during radiotherapy. Severe oral mucositis can seriously affect patients’ quality of life and compliance with radiotherapy. The aim of this study was to identify the risk factors
Zhibing Liu   +7 more
doaj   +2 more sources

Efficacy of Oral Cryotherapy in the Prevention of Oral Mucositis Associated with Cancer Chemotherapy: Systematic Review with Meta-Analysis and Trial Sequential Analysis

open access: yesCurrent Oncology, 2021
Background: This review aimed to evaluate the efficacy of oral cryotherapy in the prevention of chemotherapy-induced oral mucositis using meta-analysis and trial sequential analysis, as well as to assess the quality of the results by the Grading of ...
Ali Hatem Manfi Al-Rudayni   +4 more
doaj   +2 more sources

Management of Oral Mucositis in Children With Malignant Solid Tumors [PDF]

open access: goldFrontiers in Oncology, 2021
Introduction In recent years, the use of intensive regimens for the treatment of pediatric cancer has led to a marked improvement in patient survival. However, these treatments are associated with an increase in toxic effects.
Giorgio Attinà   +7 more
openalex   +2 more sources

Chemotherapy-induced oral mucositis is associated with detrimental bacterial dysbiosis

open access: yesMicrobiome, 2019
Background Gastrointestinal mucosal injury (mucositis), commonly affecting the oral cavity, is a clinically significant yet incompletely understood complication of cancer chemotherapy.
Bo-Young Hong   +15 more
doaj   +2 more sources

Clinical assessment of oral mucositis and candidiasis compare to chemotherapic nadir in transplanted patients [PDF]

open access: diamondBrazilian Oral Research, 2014
Oral mucositis is a chief complication in patients undergoing hematopoietic stem cell transplantation (HSCT). It is considered a toxic inflammatory reaction that interferes with the patient’s recuperation and quality of life. Oral candidiasis is a common
PATUSSI Cleverson   +4 more
doaj   +2 more sources

Characterization of a novel dual murine model of chemotherapy-induced oral and intestinal mucositis

open access: yesScientific Reports, 2023
Oral and intestinal mucositis are debilitating inflammatory diseases observed in cancer patients undergoing chemo-radiotherapy. These are devastating clinical conditions which often lead to treatment disruption affecting underlying malignancy management.
Ali I. Mohammed   +6 more
doaj   +2 more sources

An increase in Fusobacterium is associated with the severity of oral mucositis after radiotherapy [PDF]

open access: yesScientific Reports
Radiotherapy is a common treatment for head and neck cancer but often causes oral mucositis, which reduces quality of life. Recent studies suggest that radiotherapy affects the oral microbiota, but whether it contributes to the severity of mucositis has ...
Atsushi Ue   +9 more
doaj   +2 more sources

Global methylation in relation to methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia. [PDF]

open access: yesPLoS ONE, 2018
BackgroundChildren with acute lymphoblastic leukemia (ALL) often suffer from toxicity of chemotherapeutic drugs such as Methotrexate (MTX). Previously, we reported that 20% of patients receiving high-dose MTX developed oral mucositis. MTX inhibits folate
Natanja Oosterom   +7 more
doaj   +8 more sources

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