Results 41 to 50 of about 213,434 (307)
Proliferating Cell Nuclear Antigen in Premalignancy and Oral Squamous Cell Carcinoma [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: Cancer has multifactorial aetiology and is a multistep process involving initiation, promotion and tumour progression. Cellular proliferation is one of the important indicators for the biologic aggressiveness of a malignant lesion.
Chandrashekar Poosarla +5 more
doaj +1 more source
Global Medical Genetics, 2022 Because of active advancement in the field of biomedicine, people have in-depth knowledge of biological nature of malignant tumors and are able to recognized the overexpression of different molecules such as vascular endothelial growth factor receptor ...
Himanshu Singh, Vedant Patel
doaj +1 more source
Epigenetics in oral squamous cell carcinoma
Journal of Oral and Maxillofacial Pathology, 2017 Oral squamous cell carcinoma (OSCC) is the most common type of oral neoplasm, accounting for over 90% of all oral malignancies and 38% of head and neck tumors. Worldwide, OSCC is the eighth most common human cancer, with more than 500,000 new cases being diagnosed every year with a fairly onerous prognosis, encouraging further research on factors that ...
Hema, K N +3 more
openaire +3 more sources
Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]
, 2016 The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin +2 more
core +2 more sources
Notch1 in oral squamous cell carcinoma.
Histology and histopathology, 2017 Notch signaling has been reported to be involved in several types of malignant tumors. However, the role and activation mechanisms of Notch signaling in oral squamous cell carcinoma (OSCC) remain poorly characterized. The present review focuses on the dual role of Notch signaling in OSCC. A number of expression and functional analyses demonstrated that
Yoshida, Ryoji +3 more
openaire +3 more sources
Non-coding RNAs in saliva: emerging biomarkers for molecular diagnostics. [PDF]
, 2015 Saliva is a complex body fluid that comprises secretions from the major and minor salivary glands, which are extensively supplied by blood. Therefore, molecules such as proteins, DNA, RNA, etc., present in plasma could be also present in saliva.
Majem, Blanca +3 more
core +4 more sources
Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer. [PDF]
, 2013 The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the induction of pluripotency in terminally differentiated somatic cells.
Agaimy, Abbas +14 more
core +6 more sources
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Journal of Oral Biology and Craniofacial ResearchBackground: Oral squamous cell carcinoma is a common cancer of head and neck region with poor prognosis and may sometimes show a premalignant stage. Cell-cell adhesion molecules play an important role in the process of malignant transformation.
Dhanusree Kani +5 more
doaj +1 more source
Tumor Biology, 2017 Oral squamous cell carcinoma is a common and lethal malignancy affecting the head and neck region. CCAT2 (colon cancer–associated transcript 2) gene is affiliated with long non-coding RNAs, which are often found to have important regulatory roles in ...
Yuji Ma +4 more
doaj +1 more source