Results 121 to 130 of about 1,747,691 (292)

Feasibility of Oral Rabies Vaccination of Dogs in Mexico

Tropical Medicine and Infectious Disease
Mexico has not only successfully eliminated dog-mediated human rabies in recent years, but also the last rabies case in a dog infected with the canine variant of the rabies virus was reported in 2016.
Verónica Gutiérrez Cedillo, Luis Antonio Montoya Mondragón, Jose Ramón Fernández Colín, Katharina Bobe, Ad Vos, Luis Armando Lecuona Olivares, Ruy López Ridaura   +6 more
doaj   +1 more source

Induction of Transmucosal Protection by Oral Vaccination with an Attenuated Chlamydia. [PDF]

Infect Immun, 2023
Wang Y, He R, Winner H, Gauduin MC, Zhang N, He C, Zhong G.   +6 more
europepmc   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

A dual-gene-deleted ASFV Lv17/WB/Rie1-ΔCD candidate administered orally to wild boar confers DIVA-compatible protection against virulent challenge

Veterinary Quarterly
African swine fever (ASF) continues to expand worldwide. Recent detection in wild boar in Spain highlights the urgent need for effective control tools, with oral vaccination as a key priority.
Jose A. Barasona, Aleksandra Kosowska, Gabriela González-García, Marta Díaz-Frutos, Giulia Franzoni, Paola Nicolussi, Nestor Porras, Mónica Sánchez-Segovia, Daniel De Antonio-Gómez, Paloma Rueda, Sandra Barroso-Arévalo   +10 more
doaj   +1 more source

The Effect of Vaccination on Children's Physical and Cognitive Development in the Philippines [PDF]

We use data from the Cebu Longitudinal Health and Nutrition Survey in the Philippines to link vaccination in the first two years of life with later physical and cognitive development in children.
David E. Bloom, David Canning, Erica Seigner   +2 more
core  

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Evaluation of Bait Acceptance and Immune Response in a Local Dog Population During an Oral Rabies Vaccination Field Study in Cambodia

Tropical Medicine and Infectious Disease
(1) Background: Dog-mediated human rabies remains a serious public health problem in Cambodia, partially due to the high abundance of dogs. As most dogs are free-roaming and cannot easily be handled and restrained, the rabies vaccination coverage is very
Bengthay Tep, Sochetra Hak, Nouv Sophorn, Sin Grandy, Ad Vos, Dim Kanan, Kinzang Dukpa   +6 more
doaj   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Oral vaccination as a potential strategy to manage chronic wasting disease in wild cervid populations. [PDF]

Front Immunol, 2023
Napper S, Schatzl HM.
europepmc   +1 more source

Edible Vaccine - The Future of Oral Vaccination [PDF]

, 2019
Edible vaccine is cost effective, easy in administration, easy in storage and safe vaccine delivery system. Edible vaccines are prepared by molecular pharming using the science of genetic engineering. Selected genes which are pathogenic can be isolated from the source and then introduced into the plants. That plant is now called transgenic plant and it
openaire   +1 more source