Results 101 to 110 of about 100,059 (161)
COVID-19: should oral vaccination strategies be given more consideration? [PDF]
Mehan A, Venkatesh A, Girish M.
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B memory cell responses to LPS, IVP and IpaB antigen after oral vaccination with Shigella sonnei vaccine candidates WRSs2 and WRSs3. [PDF]
Venkatesan MM +4 more
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Medical Hypotheses, 2000
Otosclerosis is a genetically based disease in which the development of autoimmune mechanisms can lead to its clinical expression. Anti-type II collagen antibodies have been found in otosclerotic patient serum. The first clinically unexpressive phase of the disease can be diagnosed from a family history and ON-OFF stapedial reflexes with evidence of an
M A, Lopez-Gonzalez, F, Delgado
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Otosclerosis is a genetically based disease in which the development of autoimmune mechanisms can lead to its clinical expression. Anti-type II collagen antibodies have been found in otosclerotic patient serum. The first clinically unexpressive phase of the disease can be diagnosed from a family history and ON-OFF stapedial reflexes with evidence of an
M A, Lopez-Gonzalez, F, Delgado
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1989
Shigellae cause intestinal disease by invading the colonic epithelium. Intracellular multiplication and intercellular spread of these organisms results in mucosal lesions and inflammation of the lamina propria (LaBrec et al. 1964). These lesions are usually confined to the colon, and they are responsible for the bloody, mucoid stools characteristic of ...
T L, Hale, S B, Formal
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Shigellae cause intestinal disease by invading the colonic epithelium. Intracellular multiplication and intercellular spread of these organisms results in mucosal lesions and inflammation of the lamina propria (LaBrec et al. 1964). These lesions are usually confined to the colon, and they are responsible for the bloody, mucoid stools characteristic of ...
T L, Hale, S B, Formal
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The oral microbiome and vaccine efficacy
Medical Hypotheses, 2022The immune response elicited by vaccines is crucial in determining their eventual efficacy. The human microbiome, in particular, that of the gut has been demonstrated to influence the immunogenicity of vaccines delivered by both the oral and non-oral routes.
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Interference of oral poliovirus vaccine on RIT 4237 oral rotavirus vaccine
European Journal of Epidemiology, 1988A vaccination trial, performed on 86 3-month-old infants, has shown that the ability of the RIT 4237 live attenuated rotavirus strain to induce seroconversion is dramatically reduced when administered with live poliovirus vaccine. In a subsequent trial performed on 93 infants the attempt to overcome the poliovirus interference by administering two ...
GIAMMANCO G +7 more
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Journal of Controlled Release, 2000
Oral vaccination of animals and man, to provide effective mucosal and/or systemic immunity, is largely ineffective. This is due mainly to the very small quantity of antigen that survives degradation in the intestine and that crosses the intestinal wall.
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Oral vaccination of animals and man, to provide effective mucosal and/or systemic immunity, is largely ineffective. This is due mainly to the very small quantity of antigen that survives degradation in the intestine and that crosses the intestinal wall.
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Microparticles for oral delivery of vaccines
Expert Opinion on Drug Delivery, 2005Nonreplicating antigens are poorly immunogenic when given orally, either due to their degradation in the gastrointestinal tract or because they are not efficiently taken up in the gut. Studies in laboratory animals have clearly demonstrated that microparticles can significantly improve the immunogenicity of orally administered antigens.
George, Mutwiri +2 more
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