Results 101 to 110 of about 257,176 (353)

Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems [PDF]

, 2014
Cervical cancer is the second-most-common cause of malignancies in women worldwide, and the oncogenic activity of the human papilloma virus types (HPV) E7 protein has a crucial role in anogenital tumors.
Atyabi, F., Ghaemi, A., Gorji, A., Kalhor, H.R., Kelishadi, M., Moradi, A., Sajadian, A., Tabarraei, A., Tahamtan, A.   +8 more
core   +3 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Uptake of three doses of HPV vaccine by primary school girls in Eldoret, Kenya : a prospective cohort study in a malaria endemic setting [PDF]

, 2018
Background: All women are potentially at risk of developing cervical cancer at some point in their life, yet it is avoidable cause of death among women in Sub- Saharan Africa with a world incidence of 530,000 every year.
Kirop, Elijah, Mabeya, Hillary, Menon, Sonia, Mwaliko, Emily Waleghwa, Naanyu, Violet, Orango, Omenge, Vanden Broeck, Davy, Vermandere, Heleen, Weyers, Steven   +8 more
core   +3 more sources

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Vaccines against toxoplasma gondii : challenges and opportunities [PDF]

, 2009
Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects.
Aliberti J, Angus CW, Aosai F, Aosai F, Awan KJ, Beghetto E, Bommireddy R, Bonenfant C, Boyle JP, Brinkmann V, Buxton D, Bülow R, Caetano BC, Conacher M, Cong H, Cong H, Constant SL, Couper KN, Craig W Roberts, Cui YL, Cuppari AF, Curtsinger JM, Curtsinger JM, Cutchins EC, Darcy F, Dautu G, Debard N, Debierre-Grockiego F, DeGregorio E, Denkers EY, Desolme B, Duquesne V, Echeverria PC, Elisabeth Förster-Waldl, Erik Jongert, Escajadillo A, Eskild Petersen, Fachado A, Fachado A, Flori P, Fox B, Frenkel JK, Garcia JL, Garcia JL, Gatkowska J, Gazzinelli R, Gazzinelli RT, Golkar M, Hakim FT, Igarashi M, Innes EA, Ishii K, Ishii KJ, Ismael AB, Ismael AB, Johnson LL, Jongert E, Jongert E, Jongert E, Kasper LH, Khan IA, Kijlstra A, Kodjikian L, Krahenbuhl JL, Kringel H, Letscher-Bru V, Letscher-Bru V, Leyva R, Lindsay DS, Liu Q, Lourenco EV, Lourenço EV, Martin V, McLeod R, Mishima M, Mishima M, Mohamed RM, Mévélec MN, Mévélec MN, Nicola Gargano, Nielsen HV, Nielsen HV, Petersen E, Petrovsky N, Pettersen EK, Pfefferkorn ER, Qu D, Reikvam A, Roque-Resendiz JL, Sabin AB, Sayles PC, Schaap D, Scorza T, Siachoque H, Sibley LD, Silveira C, Stanley AC, Stockinger B, Supply P, Taneja V, Vandepapelierea P, Velge-Roussel F, Velge-Roussel F, Vercammen M, Vogel N, Vyas JM, Waldeland H, Wang H, Wilkins MF, Williams MA, Xue M, Xue M, Yang CD, Yarovinsky F, Zenner L, Zhang G, Zhang J, Zimmermann S   +117 more
core   +3 more sources

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

Advanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source

Racing against COVID-19: a vaccines strategy for Europe. Bruegel Policy Contribution Issue n˚7 | April 2020 [PDF]

, 2020
The fast development of vaccines is an essential part of the long-term solution to COVID-19, but vaccine development has high costs and carries the risk of high failure rates.
Veugelers, Reinhilde, Zachmann, Georg.
core   +1 more source

Deficiency of immunity to poliovirus type 3: a lurking danger? [PDF]

, 2012
Background: Europe was certified to be polio-free in 2002 by the WHO. However, wild polioviruses remain endemic in India, Pakistan, Afghanistan, and Nigeria, occasionally causing polio outbreaks, as in Tajikistan in 2010.
Doerr, Hans W., Friedrichs, Imke, Rabenau, Holger, Reinheimer, Claudia   +3 more
core   +2 more sources

Hypersensitivity Reaction of Tongue: Oral Adverse Effect of COVID-19 Vaccine: A Case Report

, 2023
Sabarinath Balaraman, Ramya Sekar, Dhanarathna Shanmugam, Prabhu Shankar Dhayasankar   +3 more
openalex   +1 more source