Results 81 to 90 of about 251,345 (303)

A long-lasting measles epidemic in Maroua, Cameroon 2008-2009: mass vaccination as response to the epidemic. [PDF]

, 2011
A measles outbreak occurred in Maroua, Cameroon, from January 2008 to April 2009. In accordance with recent World Health Organization guidelines, an outbreak-response immunization (ORI) was conducted in January 2009.
Anker, Aylward, Centers for Disease Control and Prevention, D. A. T. Cummings, de Alencar Ximenes, Dubray, Florence Fermon, Francisco J. Luquero, Goodson, Grais, Grais, Helfand, Heloise Pham-Orsetti, Katz, Lowther, Marcelino Nimpa, Ndong Ngoe, Orenstein, Peter Strebel, Philippe E. Ngaunji, Rebecca F. Grais, Samb, Sniadack, Stephen Sosler, Waters, World Health Organization, World Health Organization, World Health Organization, World Health Organization Regional Office for Africa, World Health Organization, UNICEF, United Nations Children's Fund, World Medical Association. Declaration of Helsinki   +30 more
core   +2 more sources

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Antitumor effect of oral cancer vaccine with Bifidobacterium delivering WT1 protein to gut immune system is superior to WT1 peptide vaccine

Human Vaccines & Immunotherapeutics, 2018
Despite the revolutionary progress of immune checkpoint inhibitors (CPIs) for cancer immunotherapy, CPIs are effective only in a subset of patients. Combining CPIs and cancer vaccines to achieve better clinical outcomes is a reasonable approach since CPI
Toshiro Shirakawa, Koichi Kitagawa
doaj   +1 more source

Pre-vaccination prevalence of anogenital and oral human papillomavirus in young HIV-infected men who have sex with men. [PDF]

, 2019
The aims of this study were to: 1) determine prevalence of anogenital and oral HPV, 2) determine concordance between HPV at anal, perianal, scrotal/penile, and oral sites; and 3) describe factors associated with anogenital HPV types targeted by the 9 ...
AIDS Malignancy Consortium and Adolescent Medicine Trials Network for HIV/AIDS Interventions, Barroso, Luis F, Belzer, Marvin, Cachay, Edward R, Chi, Xiaofei, Chiao, Elizabeth Y, Da Costa, Maria, Futterman, Donna C, Gaur, Aditya H, Goldstone, Steven E, Kahn, Jessica A, Lee, Jeannette, Martinez, Jaime, Mayer, Kenneth, Ortiz Martinez, Ana P, Palefsky, Joel M, Paul, Mary E, Reirden, Daniel, Stier, Elizabeth A, Wilson, Craig M   +19 more
core   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Antigen-displaying probiotic Bacillus subtilis spores induce subtle, strain-dependent immunomodulation in fish

Frontiers in Marine Science
Despite the availability of commercial vaccines against several pathogens, infectious diseases continue to cause substantial economic losses in aquaculture.
Gabriela Gonçalves, Gabriela Gonçalves, Rafaela A. Santos, Rafaela A. Santos, Isabel M. Cerezo, Tomás Gabriel, José Dias, Rui Magalhães, Rui Magalhães, Pedro Pousão-Ferreira, Pedro Pousão-Ferreira, Paula Enes, Paula Enes, Carolina Tafalla, Aires Oliva-Teles, Aires Oliva-Teles, Ana Couto, Ana Couto, Patricia Díaz-Rosales, Cláudia R. Serra, Cláudia R. Serra   +20 more
doaj   +1 more source

Do microRNAs play a role in the activity of plant-based vaccines?

Expert Review of Vaccines, 2017
Introduction: An important trend in vaccinology is the development of oral vaccines based on genetically modified plants. Areas covered: Several studies have suggested that dietary microRNAs from plants and other organisms are bioavailable upon oral ...
Sergio Rosales-Mendoza, Jorge A. Salazar-González   +1 more
doaj   +1 more source

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu, Haozhe Ren, Hua Li, Jinghan Zhao, Miaomiao Cao, Tian Tang, Youbei Qiao, Liting Chen, Tiehong Yang, Hong Wu   +9 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals [PDF]

, 2014
Despite the important progress obtained in the treatment of some pets’ malignancies, new treatments need to be developed. Being critical in cancer control and progression, the immune system’s appropriate modulation may provide effective therapeutic ...
Finocchiaro, Liliana Maria Elena, Glikin, Gerardo Claudio   +1 more
core   +4 more sources