Results 61 to 70 of about 127,439 (309)

Oral Vaccination Reduces the Effects of Lawsonia intracellularis Challenge on the Swine Small and Large Intestine Microbiome

Frontiers in Veterinary Science, 2021
Porcine proliferative enteropathy remains one of the most prevalent diseases in swine herds worldwide. This disease is caused by Lawsonia intracellularis, an intracellular bacterial pathogen that primarily colonizes the ileum. In this study, we evaluated
Fernando L. Leite, Brittanie Winfield, Elizabeth A. Miller, Bonnie P. Weber, Timothy J. Johnson, Fred Sylvia, Erika Vasquez, Fabio Vannucci, Dana Beckler, Richard E. Isaacson   +9 more
doaj   +1 more source

Epidemiology of type 2 vaccine-derived poliovirus outbreaks between 2016 and 2020. [PDF]

, 2022
The number and geographic breadth of circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreaks detected after the withdrawal of type 2 containing oral polio vaccine (April 2016) have exceeded forecasts.Using Acute Flaccid Paralysis (AFP ...
Nicholas C Grassly, Ousmane M Diop, Tallis, Graham, Grace R Macklin, Ondrej Mach, Diop, Ousmane M, Macklin, Grace R, Ahmed, Jamal A, Grassly, Nicholas C, Mach, Ondrej, Jamal A Ahmed, O'Reilly, Kathleen M, Ajay K Goel, Goel, Ajay K, Graham Tallis, Kathleen M O'Reilly   +15 more
core   +1 more source

Live Oral Adenovirus Type 4 and Type 7 Vaccine Induces Durable Antibody Response

, 2020
Human adenoviruses (AdV) are mostly associated with minimal pathology. However, more severe respiratory tract infections and acute respiratory diseases, most often caused by AdV-4 and AdV-7, have been reported.
Nicos Karasavvas, Jun Hang, Robert A. Kuschner, Shannon D. Walls, Anima Adhikari, Christopher A. Myers, Yu Yang, Paul C. F. Graf, Natalie D. Collins, Richard G. Jarman, Leonard N. Binn   +10 more
core   +1 more source

Costs of illness due to cholera, costs of immunization and cost-effectiveness of an oral cholera mass vaccination campaign in Zanzibar [PDF]

, 2012
BACKGROUND: The World Health Organization (WHO) recommends oral cholera vaccines (OCVs) as a supplementary tool to conventional prevention of cholera. Dukoral, a killed whole-cell two-dose OCV, was used in a mass vaccination campaign in 2009 in Zanzibar.
Claire-Lise Chaignat, Duintjer Tebbens Radboud J., Rita Reyburn, Weiss Mitchell G., Schaetti, C., Radboud J Duintjer Tebbens, Weiss, M. G., Rita Reyburn (130140), Khatib, A. M., Reyburn, R., Ahmed M. Khatib (130136), Mitchell G Weiss, Hutubessy Raymond, Schaetti Christian, Ahmed M Khatib, Claire-Lise Chaignat (127845), Raymond Hutubessy (130149), Ali, S. M., Khatib Ahmed M., Mitchell G. Weiss (130129), Chaignat Claire-Lise, Ali Said M., Hutubessy, R., Reyburn Rita, Christian Schaetti (130127), Chaignat, C. L., Raymond Hutubessy, Christian Schaetti, Said M Ali, Duintjer, Tebbens, Said M. Ali (130132), Radboud J. Duintjer Tebbens (130144)   +31 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Evidence and guidance on vaccine safety and effectiveness in subpopulations [PDF]

, 2011
This dissertation examines post-licensing vaccine safety and effectiveness against two major respiratory diseases in specific subpopulations, with emphasis on safety.
Mak, Tippi
core   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

Advanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang   +9 more
wiley   +1 more source

Long-term effectiveness against cholera of oral killed whole-cell vaccine produced in Vietnam.

, 2006
We assessed the long-term protection afforded by a killed whole-cell oral cholera vaccine produced in Vietnam. A mass immunization of children and adults with the killed whole-cell oral cholera vaccine was undertaken in half of the communes of Hue ...
Park, Jin-Kyung, Son, Nguyen Dinh, Holmgren, Jan,, Canh, Do Gia, Thiem, Vu Dinh, Deen, Jacqueline L, Ali, Mohammad, Holmgren, Jan, Clemens, John D, Hoa, Nguyen Thai, von Seidlein, Lorenz, Anh, Dang Duc, Danovaro-Holliday, M Carolina, Danovaro-Holliday, M. Carolina, Clemens, John D., Deen, Jacqueline L.   +15 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source