Results 81 to 90 of about 31,558 (310)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Are Pesticide Residues Found in the Oranges Produced in Sari? [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Today, ensuring food security for the inhabitants of the earth, and preserving agricultural production from destruction due to drought, pests, and diseases, seems more necessary than ever.
Narges Mazloomi, Ebrahim Salehifar, Mohammadhosein Esfahanizadeh, Hashem Ghezelsofla, Keyvan Mahdavi Mashaki, Esmaeil Babanezhad, Laleh Karimzadeh   +6 more
doaj  

Vantagem competitiva para micro, pequenas e médias empresas: clusters e APLs. Competitive advantage for SMes: clusters and LPA

, 2006
Micro, small, and medium-sized companies, as a result of globalization and its impositions, have been seeking to achieve competitive advantage for their survival in the market.
Oranges Cezarino Luciana
core  

Interface Between Industry 4.0 and Sustainability: A Systematic Review

, 2019
This paper explores the relationship between the concepts of industry 4.0 and sustainability as a contribution to the development of more sustainable production systems.
Stocco, Lucas, Oranges Cezarino, Luciana, Luciana Oranges Cezarino, Lucas Conde Stocco, Lucas Stocco   +4 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

DA PROBLEMÁTICA DA JUDICIALIZAÇÃO DO RISCO HIDROLÓGICO - THE PROBLEM OF THE JUDICIALISATION OF HYDROLOGICAL RISK

, 2021
The hydrological risks, greatly increased in the last years by some drought periods, influenced many judicial decisions that caused default in the MCP, which became paralyzed due to the difficulty of compliance with the CCEE contracts.
Luciana Oranges Cezarino, Adhemar Ronquim Filho   +1 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

The United States Orange Industry: Declining Production and Climbing Imports

EDIS
The US orange industry has been grappling with declining production since the early 2000s due to the outbreak of the Huanglongbing disease and various other challenges. To meet the market demand, the United States increasingly relies on imports, notably
A. Malek Hammami, Yi Li, Zhengfei Guan
doaj   +1 more source

Comparison postharvest quality of conventionally and organically grown ‘Washington Navel’ oranges

Journal of Applied Botany and Food Quality, 2013
This study aimed to compare postharvest quality of conventionally and organically grown ‘Washington Navel’ oranges. Oranges from the conventional and certified organic citrus orchards were harvested at commercial maturity and kept at 4°C for 5 months ...
Elif Çandır, Müge Kamiloğlu, Durmuş Üstün, Gülcan Tuğçe Kendir   +3 more
doaj   +1 more source

O DESAFIO DA IMPLANTAÇÃO DE UM PLANO ESTRATÉGICO EM UMA MICROEMPRESA FAMILIAR DO SETOR ALIMENTÍCIO [PDF]

, 2011
O Planejamento Estratégico é uma ferramenta administrativa muito utilizada em organizações na atualidade. O ambiente acirrado e a profissionalização dos setores têm feito as pequenas empresas, principalmente as familiares, a refletirem sobre sua ...
Cezarino, Luciana Oranges, Sudo, Barbara Tatiane, Luciana Oranges Cezarino, Barbara Tatiane Sudo   +3 more
core   +1 more source