Results 61 to 70 of about 31,558 (310)

Kebaikan Orang-Orang Kafir

open access: yesAl-Kauniyah, 2022
Penelitian ini dilatar belakangi oleh perdebatan klise setiap tahunnya antara umat muslim dan nasrani, yaitu hari raya Natal. Perdebatan tentang mengucapkan selamat Natal yang terus-menerus mengalir menjadikan nya semakin merembet menuju celah-celah permasalahan lain, hingga pada puncaknya, bermuara pada surga dan neraka. Narasi “yang penting baik sama
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Comparative Analysis of Foot Sole Classification Models: Evaluating Logistic Regression, SVM, and Random Forest

open access: yesJournal of Applied Informatics and Computing
Accurate sole classification and types can aid applications in healthcare, sports, and biometrics such as diagnosis of high arch or flat foot disease, as well as in improved design of custom orthotics and enhanced gait analysis to improve sports ...
Trie Dinda Maharani Purba, Imam Yuadi
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Dynamic Capabilities: financial and non-financial indicators of sustainable supply chains

open access: yes, 2015
Dynamic capabilities are a difficult construct to measure, in this article we present a proposal for measuring organizational performance indicators with financial and non-financial ...
oranges cezarino
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Antonio Carioti (a cura di), Luciano Canfora. Intervista sul potere, Laterza, Roma-Bari 2013. Un volume di pp. 282.

open access: yes, 2013
Recensione del volume di A. Carioti, Luciano Canfora. Intervista sul potere, Roma-Bari 2013, 1-282, ISBN:978-88-581-0894-9.Review of A. Carioti, Luciano Canfora.
Oranges, Annabella
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Euthyna e/o Eisanghelia: il processo di Cimone

open access: yes, 2013
This paper examines the legal procedure followed in Cimon’s trial, which took place at the end of the military campaign against Thasos (465/4-463/2 B.C.).
Oranges, Annabella
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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